Introduction: During paediatric resuscitation it is essential to be able to estimate the child's weight as it determines drug doses and equipment sizes. Age and length-based estimations exist, with age-based estimations being especially useful in the preparation phase and the length-based Broselow tape having weight-based drug doses and equipment already assigned via a colour code system. The aim of this study was to compare the actual recorded weights of Australian children to the predicted weights using the original and updated APLS, Luscombe and Owens and Best Guess formulae and the Broselow tape.
Method: A retrospective observational study of children attending an Australian tertiary children's hospital.
Results: From 49,565 patients extracted from the database, 37,114 children with age and weight and 37,091 children with age and height recorded were included in the analysis. Best Guess was the most accurate, with the smallest overall mean difference 0.86 kg. For <1 year old, Broselow tape was the most accurate (mean difference -0.43 kg), Best Guess was the most accurate for ages 1-5 years and 11-14 years (mean difference 0.27 and 0.20 kg respectively), and the updated APLS formula was the most accurate for 6-10 year-old (mean difference 0.42 kg). The Broselow tape was able to only classify 48.9% of children into the correct weight colour band.
Conclusions: For an age-based weight estimation, in infants less than one year the new APLS formula is the most accurate and over one year the Best Guess formulae should be used.
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http://dx.doi.org/10.1016/j.resuscitation.2013.11.024 | DOI Listing |
Pharmaceutics
November 2024
School of Pharmacy, Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA 15282, USA.
Skin inflammation represents a hallmark of many skin conditions, from psoriasis to eczema. Here, we present a novel microemulsion formulation for delivering a low dose of potent immunosuppressant, tacrolimus, to the skin for local inflammation control. The efficacy of topically delivered tacrolimus in controlling skin inflammation can be enhanced by packaging it into microemulsions.
View Article and Find Full Text PDFFront Artif Intell
December 2024
Center for Population Health Data Science, NYC Department of Health and Mental Hygiene, New York City, NY, United States.
Introduction: It is not uncommon to repurpose administrative food data to create food environment datasets in the health department and research settings; however, the available administrative data are rarely categorized in a way that supports meaningful insight or action, and ground-truthing or manually reviewing an entire city or neighborhood is rate-limiting to essential operations and analysis. We show that such categorizations should be viewed as a classification problem well addressed by recent advances in natural language processing and deep learning-with the advent of large language models (LLMs).
Methods: To demonstrate how to automate the process of categorizing food stores, we use the foundation model BERT to give a first approximation to such categorizations: a best guess by store name.
Science
January 2025
Alfred Wegener Institute, Helmholtz Centre for Polar and Marine Research, Bremerhaven, Germany.
In 2023, the global mean temperature soared to almost 1.5 kelvin above the preindustrial level, surpassing the previous record by about 0.17 kelvin.
View Article and Find Full Text PDFEduc Psychol Meas
October 2024
Curriculum Associates, North Billerica, USA.
Rapid-guessing behavior in data can compromise our ability to estimate item and person parameters accurately. Consequently, it is crucial to model data with rapid-guessing patterns in a way that can produce unbiased ability estimates. This study proposes and evaluates three alternative modeling approaches that follow the logic of the effort-moderated item response theory model (EM-IRT) to analyze response data with rapid-guessing responses.
View Article and Find Full Text PDFAnn Am Thorac Soc
October 2024
Michigan State University College of Nursing, East Lansing, Michigan, United States.
Rationale: Under-perception of asthma symptoms is associated with poor asthma outcomes.
Objective: We assessed the effects of a behavioral intervention for improving perception of airflow limitation and asthma outcomes.
Methods: A two-arm randomized controlled trial compared peak expiratory flow (PEF) feedback versus supportive counseling.
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