Conference report: hot topics in antibody-drug conjugate development.

Bioanalysis

Novartis Pharmaceuticals, Clinical Pharmacology, Oncology Business Unit, East Hanover, NJ, USA.

Published: December 2013

American Association of Pharmaceutical Scientists National Biotechnology Conference Sheraton San Diego Hotel and Marina, San Diego, CA, USA, 19-23 May 2013 The National Biotechnology Conference, is a premier meeting for biotechnology professionals covering a broad range of hot topics in the biotechnology industry. Attracting participants from academia, industry and regulatory, this meeting features sessions that aim to address emerging subjects of interest and allows for open exchange between scientists. The 2013 conference featured leading researchers in the fields of antibody-drug conjugates (ADCs) and immunogenicity. Herein, we present a summary of the ADC hot topics, including bioanalytical and PK considerations, quantitative evaluation of the impact of immunogenicity and ADME to understand ADC drug-drug interactions, and clinical considerations for ADC development. This article aims to summarize the recommendations that were made by the speakers during various sessions throughout the conference.

Download full-text PDF

Source
http://dx.doi.org/10.4155/bio.13.276DOI Listing

Publication Analysis

Top Keywords

hot topics
12
national biotechnology
8
biotechnology conference
8
san diego
8
conference
5
conference report
4
report hot
4
topics antibody-drug
4
antibody-drug conjugate
4
conjugate development
4

Similar Publications

Background: Since the emergence of the hot topic of "ferroptosis," numerous studies have explored its role in hepatocellular carcinoma (HCC), revealing its significance in the disease's pathogenesis, progression, and treatment. However, there remains a significant gap in the quantitative analysis of ferroptosis in HCC. Therefore, this study aims to comprehensively assess the research progress and evolution in this field through bibliometric and citation analysis.

View Article and Find Full Text PDF

Bioinspired Carbon-Silver Sulfide Scaffold with Synergistic Enhanced Light Capture and Anti-Biofouling Property for Stable Solar Steam Generation.

Small

December 2024

Anhui Province Key Laboratory of Advanced Catalytic Materials and Reaction Engineering, School of Chemistry and Chemical Engineering, Hefei University of Technology, Hefei, 230009, China.

Carbon material is a hot topic in solar evaporation. Due to the widely distributed microorganisms in natural water, biofouling has limited the actual application of solar evaporation material. Although carbon material lacks of nutrition for microbe, it is still vulnerable to biofouling because of the efficient pollutant adsorption property.

View Article and Find Full Text PDF

Background: Online health-related misinformation poses a serious threat to public health. As the coronavirus disease 2019 (COVID-19) pandemic aggravated the spread of misinformation regarding COVID-19, relevant research has surged.

Objective: To systematically summarize Chinese and English articles regarding health-related misinformation about COVID-19 on social media and quantitatively describe research progress.

View Article and Find Full Text PDF

Background: Diabetes has emerged as the foremost public health challenge of the 21st century, with a notable shift towards managing it through an inflammatory lens. This study seeks to investigate the role of NLRP3 infalmmasome in diabetes over the past ten years, leveraging bibliometric analysis to pinpoint prevailing trends, underscore critical focal points, and establish a roadmap for subsequent research endeavors.

Method: A literature search was conducted based on the SCI-E database, and all recorded results were downloaded in plain text format for subsequent analysis.

View Article and Find Full Text PDF

Background: Chemotherapy is crucial in the management of tumors, but challenges such as chemoresistance and adverse reactions frequently lead to therapeutic delays or even premature cessation. A growing body of research underscores a profound connection between the gut microbiota (GM) and cancer chemotherapy (CC). This paper aims to pinpoint highly influential publications and monitor the current landscape and evolving trends within the realm of GM/CC research.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!