Effects of zinc on the content of chemical elements in the liver of rats during early stages of obesity.

Bull Exp Biol Med

Research Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences; A. V. Nikolaev Institute of Inorganic Chemistry, Siberian Division of the Russian Academy of Sciences, Novosibirsk; Research Institute of Biocides and Nanobiotechnology, Moscow, Russia.

Published: December 2013

In rats with slight alimentary obesity, the content of chemical elements in the liver did not differ from normal, but the correlations between these elements were changed, which attested to metabolic disorders. Additional zinc dose administered to rats receiving lipid-rich rations did not affect animal body weights and content of chemical elements (including zinc) in the liver, but corrected correlations between the elements. Active contribution of strontium, bromine, and rubidium to interactions between the elements in the liver necessitates studies of their role in biological processes, specifically, in initiation and development of obesity.

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http://dx.doi.org/10.1007/s10517-013-2309-8DOI Listing

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