Correlation between circulating corticosterone and protein carbonylation in the liver after short-term hypokinesia.

Bull Exp Biol Med

Chelyabinsk State Medical Academy, Ministry of Healthcare of the Russian Federation, Chelyabinsk, Russia.

Published: December 2013

We studied the correlation of the concentration of circulating corticosterone and parameters of dexamethasone suppression test with the level of protein carbonylation in the liver after short-term hypokinesia. Increasing hypokinesia duration was followed by worsening of disturbances in the hypothalamic-pituitary-adrenal system via a negative feedback mechanism and enhanced protein carbonylation in the liver.

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http://dx.doi.org/10.1007/s10517-013-2307-xDOI Listing

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