Fixed-ratio schedules are widely used in behavioral research. Although fixed-ratio schedules often conjure up relationships to work and effort, little is known about effort-related measures in these schedules. Early research had shown that force and effort of operant behavior vary systematically during the execution of ratio schedules, and the goal of the present study was to revisit early research on force dynamics in fixed-ratio schedules. Four rats earned sucrose by pressing an isometric force transducer. Presses produced sucrose after ten or twenty responses. In general, the force of responses increased then decreased systematically across the ratio. The possibility that decreases in force during ratio execution was due to a trade-off with the differential reinforcement of short inter-response times (IRT) was investigated in an additional condition where sucrose was made available according to a tandem fixed-ratio 19 inter-response (IRT)> t schedule. The tandem IRT requirement did not eliminate decreasing trends in force across the ratio; unexpectedly, the tandem requirement did eliminate increases in force early in the ratio, which may reflect sequence-level organization operating in the control of force dynamics.
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http://dx.doi.org/10.1016/j.beproc.2013.11.005 | DOI Listing |
eNeuro
January 2025
Department of Pharmacology, Addiction Science and Toxicology, University of Tennessee Health Science Center, Memphis, Tennessee 38163
The social environment has long been recognized to play an important role in substance use, which is often modeled in rodents using operant conditioning. However, most operant chambers only accommodate one rodent at a time. We present PeerPub-a unique social operant chamber.
View Article and Find Full Text PDFJ Comp Psychol
November 2024
University of Kentucky, Department of Psychology.
Serial pattern learning describes behavior in which a subject anticipates not only the time and effort needed for the next reinforcer but also the pattern of time and effort to reinforcers after the first. Chandel et al. (2021) found that pigeons left a progressive (increasing ratio) schedule earlier than would have been optimal.
View Article and Find Full Text PDFNeuropharmacology
March 2025
Program in Neuroscience, Indiana University, Bloomington, IN, USA; Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA; Gill Institute for Neuroscience, Indiana University, Bloomington, IN, USA. Electronic address:
Cannabinoid CB agonists show promise as analgesics because they lack unwanted side effects associated with direct activation of CB receptors. CB receptor activation suppresses pathological pain in animal models, but the types of pain that best respond to CB agonists are incompletely understood. This gap in knowledge may contribute to failures in clinical translation.
View Article and Find Full Text PDFDrug Alcohol Depend
January 2025
Drug Design and Synthesis Section, Molecular Targets and Medications Discovery Branch, NIDA and NIAAA, Bethesda, MD, USA.
Background: Kappa-opioid receptors (KOR) are hypothesized to be involved in mediating ongoing methamphetamine self-administration. Previous rat studies have demonstrated that treatment with the KOR antagonist nor-binaltorphimine (nor-BNI) decreases methamphetamine self-administration. However, KOR antagonist effects on methamphetamine self-administration in nonhuman primates are unknown.
View Article and Find Full Text PDFJ Exp Anal Behav
November 2024
Instituto Continuum, Londrina, Paraná, Brazil.
Four experiments assessed the effects of simultaneous point gains and losses on human responding on a moving response button. Experiments 1 and 2 examined the effects of point loss arranged in variable-time (VT) and variable-interval (VI) schedules on persistence. For that purpose, a multiple schedule was in force.
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