Purpose: The occurrence of gastrocutaneous fistula (GCF) is a well-known complication after gastrostomy tube placement. We explore multiple factors to ascertain their impact on the rate of persistent GCF formation.
Methods: We retrospectively reviewed patient records for all gastrostomies (GT) constructed at our institution from 2007 to 2011. Association of GCF with method of placement, concomitant fundoplication, neurologic findings, duration of therapy, and demographics was evaluated using logistic regression.
Results: Nine hundred fifty patients had GTs placed, of which 148 patients had GTs removed and 47 (32%) of 148 required surgical closure secondary to persistent GCF. Laparoscopic and open procedures comprised 79 (53%) of 148 and 69 (47%) of 148, respectively. Seventeen (22%) patients in the laparoscopic group developed persistent GCF, compared to 30 (43%) in the open group (P=0.035, OR=2.52). Seventy-one patients had concomitant Nissen fundoplication. Thirty-one (44%) developed GCF, compared to 16 (21%) without a Nissen (P=0.002, OR=4.94). Patients with button in place for 303 days had persistent GCF incidence of 23%, compared to 45% at 540 days (P<0.001, OR=3.51) and 50% at 850 days (P=0.011, OR=4.51). Patients with device placed at 1.8 months of age were more likely to develop GCF compared to those with device placed at 8.9 months of age (P=0.017, OR=2.35).
Conclusion: Open operations, concurrent Nissen and younger age at placement were all statistically significant factors causing persistent GCF.
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http://dx.doi.org/10.1016/j.jpedsurg.2013.06.001 | DOI Listing |
J Psychiatr Res
November 2024
Department of Neurology, The Second Affiliated Hospital of Chengdu Medical College, China National Nuclear Corporation, 416 Hospital, Chengdu, Sichuan, 610000, China. Electronic address:
This study aimed to investigate the association between global cognitive functioning (GCF) and fear of falling (FOF) in a large population-based sample of adults aged 45 years and older. A total of 2997 and 2012 participants from the original sample were included in the cross-sectional and prospective models, respectively. Participants were re-coded to 'no FOF' and 'FOF' based on their self-reported responses, and those who reported FOF at follow-up were defined as the newly-developed FOF group.
View Article and Find Full Text PDFCureus
October 2024
Department of Orthodontics, Kothiwal Dental College and Research Centre, Moradabad, IND.
Introduction: A persistent systemic hyperglycemia as observed in patients with type 2 diabetes mellitus (DM) has been associated with periodontal inflammation. Therefore, the primary objective of the present study was to assess the levels of thromboxane B2 (TXB2) and prostaglandin E2 (PGE2) in the gingival crevicular fluid (GCF) of type 2 DM and non-diabetic patients with chronic periodontitis. The secondary objectives were to correlate these levels with various parameters such as age, gender, glycated hemoglobin (HbA1c) levels, probing depth (PD), and fasting blood sugar levels and to determine the significant predictors for PGE2 and TXB2 levels.
View Article and Find Full Text PDFInt J Surg Case Rep
December 2024
Division of Surgery, Kirk Kerkorian School of Medicine at UNLV, Las Vegas, NV, United States of America. Electronic address:
Introduction: Persistent gastrocutaneous fistula (GCF) remains a rare but known complication after gastrostomy tube removal. In children, the gold standard of treatment is surgical through an open fistula takedown. Adults, on the other hand, have a much smaller incidence rate, creating a more difficult dilemma in management.
View Article and Find Full Text PDFGlob Chang Biol
October 2024
College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Plant roots represent about a quarter of global plant biomass and constitute a primary source of soil organic carbon (C). Yet, considerable uncertainty persists regarding root litter decomposition and their responses to global change factors (GCFs). Much of this uncertainty stems from a limited understanding of the multifactorial effects of GCFs and it remains unclear how these effects are mediated by litter quality, soil conditions and microbial functionality.
View Article and Find Full Text PDFJ Periodontol
September 2024
Oral Sciences Research Group, Special Needs Unit, Department of Surgery and Medical-Surgical Specialties, School of Medicine and Dentistry, Universidade de Santiago de Compostela, Health Research Institute of Santiago (IDIS), Santiago de Compostela, Spain.
Background: Few investigations evaluated smoking's impact on the periodontal proteome. Therefore, this study aimed to analyse the influence of tobacco on the overall periodontal proteome and the differential expression of gingival crevicular fluid (GCF) proteins using sequential window acquisition of all theoretical mass spectra (SWATH-MS).
Methods: GCF samples were collected from 40 periodontitis subjects (stages III-IV).
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