Identifying which ligands might bind to a protein before crystallization trials could provide a significant saving in time and resources. LigSearch, a web server aimed at predicting ligands that might bind to and stabilize a given protein, has been developed. Using a protein sequence and/or structure, the system searches against a variety of databases, combining available knowledge, and provides a clustered and ranked output of possible ligands. LigSearch can be accessed at http://www.ebi.ac.uk/thornton-srv/databases/LigSearch.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852652 | PMC |
| http://dx.doi.org/10.1107/S0907444913022294 | DOI Listing |
Publication Analysis
Top Keywords
web server
8
ligands bind
8
ligsearch knowledge-based
4
knowledge-based web
4
server identify
4
ligands
4
identify ligands
4
protein
4
ligands protein
4
protein target
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!