AI Article Synopsis
- Adult Still's disease can have various non-specific symptoms that make it hard to diagnose; a rare presentation includes myopericarditis, which must be recognized.
- A case study highlights a 49-year-old man who experienced severe fever, joint pain, rash, and chest pain due to myopericarditis, with standard tests failing to identify the cause; ultimately, he was diagnosed with Adult Still's disease through specific lab findings.
- Treatment with corticosteroids and anakinra led to quick improvement, emphasizing the need to consider Adult Still's disease in undiagnosed systemic inflammatory conditions, as it can be severe if left untreated.
Article Abstract
Introduction: Adult Still's disease may present with multiple non-specific clinical manifestations leading to diagnostic difficulties. Presentation as initial myopericarditis is rare but must be known.
Case Report: We report a 49-year-old man who presented with the sudden onset of a high fever, arthralgia and myalgia, skin rash, dyspnea and chest pain related to a myopericarditis. Infectious, neoplastic and autoimmune diagnostic work-up was non-contributive. Adult Still's disease was discussed and confirmed by the decrease in the glycosylated fraction of ferritin. Corticosteroids followed by interleukin-1 receptor antagonist (anakinra) therapy allowed a rapid improvement in clinical and biological manifestations.
Conclusion: Adult Still's disease should be considered in any systemic inflammatory disease without a diagnosis, even with atypical manifestations, especially since it can be life-threatening in the absence of treatment.
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| http://dx.doi.org/10.1016/j.revmed.2013.06.014 | DOI Listing |
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