Aim: The study was carried out to see the diversity of oral microflora and its antibiotic sensitivity test in children of age group 6 to 12 years was carried.
Materials And Methods: Total 50 patients of age group 6 to 12 years were analyzed for their oral microflora and then checked for the antibiotic susceptibility test. The samples that were collected were incubated at 37°C for 48 hours. Once dispersed samples were taken and Gram staining was done, also they were spread on to a number of freshly prepared agar plates and incubated to allow cells to form microbial colony.
Results: The result showed microflora common in all types, Gram-positive facultative anaerobic rods and cocci. In normal children Gram-positive facultative anaerobic and fermenting cocci were predominant where as in children with caries growth of microbiota that were Gram-negative and positive, capnophilic, motile and anaerobic rods and cocci belonging to members of genera S. mutans and A. actinomycetemcomitans was seen.
Conclusion: By the present study it has been concluded that the number of bacteria determined by microscopic counts was twice as high in caries patients as in healthy sites, and also recommended that amoxicillin, ampicillin and amikacin are the most effective antibacterial drugs for the treatment of dental caries.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.5005/jp-journals-10024-1370 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Experimental Murine Periodontitis Increases Salivary Gland IgA-Producing B Cells Following Oral Dysbiosis.
Microbiol Immunol
December 2024
Department of Oral Microbiology and Immunology, Showa University Graduate School of Dentistry, Shinagawa-ku, Tokyo, Japan.
Article Synopsis
- The study explores how periodontal inflammation affects both salivary gland function and the oral microbiome, highlighting the significance of these factors in overall health.
- In an experimental model with mice, researchers noticed changes in immune cell activity in the salivary glands and alterations in the oral microbiome following induced periodontitis.
- The findings emphasize a strong connection between oral bacteria, immune responses in salivary glands, and how inflammation can disrupt oral health, providing insights into maintaining oral homeostasis.
Dynamic effects of fixed orthodontic treatment on oral health and oral microbiota: a prospective study.
BMC Oral Health
December 2024
School of Stomatology, Capital Medical University, Beijing, 100050, China.
Objective: This prospective clinical study examined the effects of fixed orthodontic appliances on oral hygiene and assessed changes in the oral microflora structure of orthodontic patients using high-throughput sequencing technology.
Methods: A total of 45 patients undergoing initial fixed orthodontic treatment were recruited from three hospitals in Beijing, China. Clinical parameters and oral hygiene habits questionnaire were recorded at pre-treatment (T0) and at a 6-month follow-up (T1).
The Oral-Gut-Brain Axis: The Influence of Microbes as a Link of Periodontitis With Ischemic Stroke.
CNS Neurosci Ther
December 2024
Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, China.
Periodontitis, a non-communicable chronic inflammation disease resulting from dysbiosis of the oral microbiota, has been demonstrated to have a positive association with the risk of ischemic stroke (IS). The major periodontal pathogens contribute to the progression of stroke-related risk factors such as obesity, diabetes, atherosclerosis, and hypertension. Transcriptional changes in periodontitis pathogens have been detected in oral samples from stroke patients, suggesting a new conceptual framework involving microorganisms.
View Article and Find Full Text PDFProspective and challenges of locally applied repurposed pharmaceuticals for periodontal tissue regeneration.
Front Bioeng Biotechnol
November 2024
Department of Oral Medicine, Periodontology, and Diagnosis, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt.
Periodontitis is a persistent inflammatory condition that causes periodontal ligament degradation, periodontal pocket development, and alveolar bone destruction, all of which lead to the breakdown of the teeth's supporting system. Periodontitis is triggered by the accumulation of various microflora (especially anaerobes) in the pockets, which release toxic substances and digestive enzymes and stimulate the immune system. Periodontitis can be efficiently treated using a variety of techniques, both regional and systemic.
View Article and Find Full Text PDFThe Role of Vitamin D3 Deficiency and Colonization of the Oral Mucosa by Yeast-like Fungi in the Pathomechanism of Psoriasis.
J Clin Med
November 2024
Department of Aesthetic Dermatology, Faculty of Health Sciences, Pomeranian Medical University in Szczecin, 70-111 Szczecin, Poland.
Psoriasis is a chronic inflammatory skin disease with complex pathogenesis and variable severity. Performed studies have indicated the impact of vitamin D3 deficiency on the pathogenesis of psoriasis and its severity. However, there is no clear evidence of the influence of the mucosal microbiome on the onset and progression of psoriasis.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!