The aim was to conduct a systematic review of studies that described the functional profile of patients with behavioral variant frontotemporal dementia (bvFTD), published between 2000 and 2013. The bibliographic search was conducted using the terms "frontotemporal dementia" and "frontotemporal lobar degeneration" in combination with "independence," "functionality," "basic activities of daily living," "disability," and scales that measure functional performance: "Disability Assessment for Dementia-DAD," "Functional Activities Questionnaire (FAQ)," "Direct Assessment of Functional Status (DAFS)." To be included in the review, the study had to mention the characterization of the functional status of patients with bvFTD in the objectives of the study, using a previously validated instrument of functional assessment. Fourteen studies met this criterion. The reviewed studies suggested that individuals with bvFTD have greater functional impairment when compared to those with other subtypes of frontotemporal lobar degeneration or Alzheimer's disease. The studies documented a significant association between cognitive impairment and measures of functionality in these patients. The cognitive profile of patients may predict faster functional decline.
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http://dx.doi.org/10.1155/2013/837120 | DOI Listing |
Geroscience
January 2025
Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA, 70808, USA.
Declines in physical and cognitive function are common in older adults. The circulating enzyme glycosylphosphatidylinositol (GPI)-specific phospholipase D1 (GPLD1) is elevated after exercise and has been associated with improved cognitive function when administered to aged mice. The purpose of this study was to investigate the relationship between GPLD1 and both cognitive function and brain structure/function in older adults with either high or low levels of physical activity.
View Article and Find Full Text PDFJ Neurointerv Surg
January 2025
Neuroscience, Valley Baptist Medical Center - Harlingen, Harlingen, Texas, USA.
Background: There is growing interest and evidence in spontaneous intracerebral hemorrhage (ICH) evacuation with minimally invasive surgery (MIS). If early ICH evacuation becomes the standard of care, training neurointerventionalists to perform MIS would expand global access to treatment. We present a retrospective analysis of patients who underwent MIS-ICH evacuation performed by interventional neurologists in collaboration with neurosurgeons.
View Article and Find Full Text PDFGut Microbes
December 2025
State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China.
Changes in the gut microbiota are associated with obesity and may influence weight loss. We are currently implementing a sustained multidisciplinary collaborative weight management (MCWM) approach to weight loss. We report significant improvements in participant health status after 6 months, along with alterations in the structure, interactions, and metabolic functions of the microbiota.
View Article and Find Full Text PDFTree Physiol
January 2025
Laboratoire de Biologie du Développement, UMR 7622, Institut de Biologie Paris-Seine (IBPS), Sorbonne Université, CNRS, F-75005 Paris, France.
Norway maple and sycamore belong to the Acer genus and produce desiccation-tolerant and desiccation-sensitive seeds, respectively. We investigated the seed germination process at the imbibed and germinated stages using metabolomic and proteomic approaches to determine why sycamore seeds germinate earlier and are more successful at establishing seedlings than Norway maple seeds under controlled conditions. Embryonic axes and embryonic axes with protruded radicles were analyzed at the imbibed and germinated stages, respectively.
View Article and Find Full Text PDFRetin Cases Brief Rep
January 2025
Chair of Ophthalmology division; Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv, Israel.
Purpose: To evaluate the potency and security of Pneumatic Vitreolysis (PVL) as the primary treatment for Full-Thickness Macular Holes (FTMHs) and provide insights into patient selection criteria and procedural outcomes.
Patients And Methods: A retrospective analysis of three clinical cases presenting with FTMHs treated initially with PVL was conducted. Cases were evaluated for anatomical and functional outcomes through comprehensive ophthalmic examination and optical coherence tomography (OCT) imaging.
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