Micropatterned polymeric nanosheets for local delivery of an engineered epithelial monolayer.

Adv Mater

WPI-Advanced Institute for Materials Research (WPI-AIMR), Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, 980-8577, Japan; Department of Life Science and Medical Bioscience, School of Advanced Science and Engineering, Waseda University, TWIns, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo, 162-8480, Japan.

Published: March 2014

Like a carpet for cells, micropatterned polymeric nanosheets are developed toward local cell delivery. The nanosheets direct morphogenesis of retinal pigment epithelial (RPE) cells and allow for the injection of an engineered RPE monolayer through syringe needles without the loss of cell viability. Such an ultrathin carrier has the promise of a minimally invasive delivery of cells into narrow tissue spaces.

Download full-text PDF

Source
http://dx.doi.org/10.1002/adma.201304183DOI Listing

Publication Analysis

Top Keywords

micropatterned polymeric
8
polymeric nanosheets
8
nanosheets local
4
local delivery
4
delivery engineered
4
engineered epithelial
4
epithelial monolayer
4
monolayer carpet
4
carpet cells
4
cells micropatterned
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!