This article reviews current literature discussing the etiology, pathophysiology, diagnosis and imaging, and conservative and surgical treatment of Charcot osteoarthropathy. The treatment of Charcot osteoarthropathy with concurrent osteomyelitis is also discussed.
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A Role of Inflammation in Charcot-Marie-Tooth Disorders-In a Perspective of Treatment?
Int J Mol Sci
December 2024
Neuromuscular Unit, Mossakowski Medical Research Institute Polish Academy of Sciences, 02-106 Warsaw, Poland.
Despite the fact that there are published case reports and model work providing evidence of inflammation in Charcot-Marie-Tooth disorders (CMTs), in clinical practice, CMT and inflammatory neuropathies are always classified as two separate groups of disorders. This sharp separation of chronic neuropathies into two groups has serious clinical implications. As a consequence, the patients harboring CMT mutations are practically excluded from pharmacological anti-inflammatory treatments.
View Article and Find Full Text PDFSurgical correction of cavus foot may promote quality of life in patients with Charcot-Marie-Tooth disease: A retrospective study.
J Foot Ankle Surg
January 2025
Department of Sports medicine, Peking University Shenzhen Hospital, Shenzhen, Guangdong Province, China. Electronic address:
Charcot-Marie-Tooth disease (CMT) is a hereditary peripheral neuropathy leading to neuromuscular impairments, muscle atrophy, and functional limitations. Currently, no specific treatment exists to restore muscle strength in patients with CMT, and the disease can be severely disabling. Surgical correction of cavus foot has been suggested as a potential intervention to alleviate pain and improve gait in selected patients.
View Article and Find Full Text PDFElectrical storm in a patient with Charcot-Marie-Tooth disease treated with radiofrequency ablation and subsequent serious complication of implantable cardioverter defibrillator implantation: a case report.
Eur Heart J Case Rep
January 2025
Department of Internal Medicine and Cardiology, Faculty of Medicine, University Hospital Ostrava, University of Ostrava, 17. listopadu 1790, 708 52 Ostrava, Czech Republic.
Background: Charcot-Marie-Tooth is the most common inherited neuromuscular disorder. Rarely, it can be associated with heart failure and various arrhythmic disturbances. This case illustrates the challenges of making decisions to prevent sudden cardiac death in a patient with Charcot-Marie-Tooth disease.
View Article and Find Full Text PDF[The place of social networks in the daily lives of caregivers in adolescent psychiatry].
Soins Psychiatr
December 2024
Service de médecine de l'adolescent, Centre hospitalier de Versailles, Hôpital André-Mignot, 11 rue de Versailles, 78150 Le Chesnay-Rocquencourt, France.
Social networks play an important role in the daily lives of adolescents, even when they are hospitalized in a child psychiatric ward. While they enable them to establish and maintain relationships, and can ease emotional tensions, they can also increase their sense of malaise. Many hospitalized young people report digital harassment, revenge porn or exposure to harmful or even dangerous content.
View Article and Find Full Text PDFCharcot-Marie-Tooth Disease Presenting in the Postpartum Period: A Case Report.
Cureus
December 2024
Clinical Neurophysiology, University Hospital of Wales, Cardiff, GBR.
Charcot-Marie-Tooth disease (CMT) is the most common hereditary peripheral neuropathy. It presents a wide range of genetic and phenotypic heterogeneity. CMT disease type 1A (CMT1A), caused by PMP22 gene duplication, represents the most common subtype of CMT in Western countries.
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