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Acardius acephalus: "headless-heartless nine-month life". | LitMetric

Acardius acephalus: "headless-heartless nine-month life".

J Obstet Gynaecol India

Department of Obstetrics and gynaecology, Midnapore Medical College, 25/H/1 Upendra Chandra Banerjee Road, Kolkata, West Bengal 54 India.

Published: December 2012

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632684PMC
http://dx.doi.org/10.1007/s13224-013-0358-6DOI Listing

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Article Synopsis
  • - The TRAP (Twin Reversed Arterial Perfusion) sequence occurs in monochorionic pregnancies where one fetus is healthy and the other is non-viable, leading to risks like high-output cardiac failure in the viable twin.
  • - A 32-year-old woman with TRAP syndrome experienced contractions and spotting at 26 weeks and underwent a cesarean section after concerns of placental abruption; her viable twin was born but later died due to prematurity complications.
  • - This case emphasizes the need for early detection and ongoing prenatal care in managing TRAP syndrome, while also calling for more research into interventions that improve outcomes for affected pregnancies.
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Background: Twin reversed arterial perfusion (TRAP) sequence is a rare complication of monochorionic multiple gestation pregnancies, in which the pump twin provides hemodynamic support to a nonviable co-twin (acardius). Fetal magnetic resonance imaging (MRI) is used to detect pump twin abnormalities, particularly brain ischemia, prior to fetal intervention to interrupt umbilical blood flow to the acardius.

Objective: To summarize the imaging findings of TRAP sequence pregnancies in a large series.

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Twin reversed arterial perfusion syndrome is a rare obstetric condition that occurs in monochorionic twin pregnancies, resulting in coexistence of a normal "pump" twin and an acardiac twin. The acardiac twin is dependent upon the normal twin to provide circulation by means of vascular anastomosis, thereby putting the pump fetus at risk of high output cardiac failure. Overall only 50% of pump twins survive.

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Background: Acardiac twinning complicates monochorionic twin pregnancies in ≈2.6%, in which arterioarterial (AA) and venovenous placental anastomoses cause a reverse circulation between prepump and preacardiac embryos and cessation of cardiac function in the preacardiac. Literature suggested four acardiac body morphologies in which select (groups of) organs fail to develop, deteriorate, or become abnormal: acephalus (≈64%, [almost] no head, part of body, legs), amorphus (≈22%, amorphous tissue lump), anceps (≈10%, cranial bones, well-developed), and acormus (≈4%, head only).

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Introduction: twin reversed arterial perfusion (TRAP) sequence is a rare anomaly that occurs in monochorionic twins with overall mortality rate ranging from 50% to 70% in the normal fetus, above all for congestive cardiac failure.

Case Report: a 31-year-old Caucasian gravida was referred to our fetomaternal medicine unit in the 25 gestational age. Ultrasound examination revealed a monochorionic, biamniotic twin pregnancy with a donor fetus showing normal morphology and growth corresponding to gestational age.

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