Asymmetric conjugate additions of branched aldehydes to vinyl sulfones promoted by sulfonamide organocatalyst 6 or 7 have been developed, allowing facile synthesis of the corresponding adducts with all-carbon quaternary stereocenters in excellent yields with up to 95% ee.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269931 | PMC |
| http://dx.doi.org/10.3390/molecules181214529 | DOI Listing |
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