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| http://dx.doi.org/10.1105/tpc.113.251113 | DOI Listing |
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Genome-Wide Identification and Expression Analysis of the Gene Family in Roses ( Jacq.).
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College of Horticulture, Gansu Agricultural University, Lanzhou 730070, China.
Calmodulin-binding transcription activator (), as one of the transcription factors, is involved in performing important functions in modulating plant stress responses and development in a Ca/CaM-driven modus. However, genome-scale analysis of has not been systemically investigated in roses. Rose ( Jacq.
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Department of Pharmacy, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, Anhui, China. Electronic address:
Vascular endothelial dysfunction is one of the leading causes of developing vascular lesions in Type 2 diabetes mellitus (T2DM). In the development of vascular lesions, when endothelial cells are stimulated by hyperglycemia, inflammation and other external conditions, endothelial cell dysfunction will occur, which promotes endothelial cells to lose its typical phenotype and gain mesenchymal characteristics, with the occurrence of endothelial-to-mesenchymal transition (EndMT). At the same time promote endothelial cell proliferation and migration, induce vascular injury.
View Article and Find Full Text PDF[Exploration of electroacupuncture at "Fengchi" (GB 20) and "Sishencong" (EX-HN 1) for attenuating learning and memory impairment in vascular dementia rats based on NMDAR/CREB/BDNF signaling pathway].
Zhongguo Zhen Jiu
December 2024
First Clinical Medicine School, Heilongjiang University of CM, Harbin 150040, China.
Objective: To explore the mechanism of electroacupuncture (EA) at "Fengchi" (GB 20) and "Sishencong" (EX-HN 1) on learning and memory impairment in vascular dementia (VD) rats by observing the influences on the N-methyl-D-aspartate receptor (NMDAR)/cyclic adenosine monophosphate response element-binding protein (CREB)/brain-derived neurotrophic factor (BDNF) signaling pathway and the excitotoxicity induced by hippocampal calcium overload.
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HDAC4 Inhibits NMDA Receptor-mediated Stimulation of Neurogranin Expression.
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The coordination of neuronal wiring and activity within the central nervous system (CNS) is crucial for cognitive function, particularly in the context of aging and neurological disorders. Neurogranin (Ng), an abundant forebrain protein, modulates calmodulin (CaM) activity and deeply influences synaptic plasticity and neuronal processing. This study investigates the regulatory mechanisms of Ng expression, a critical but underexplored area for combating cognitive impairment.
View Article and Find Full Text PDFNaHS alters synaptic plasticity proteins and enhances dendritic arborization to improve cognitive and motor deficits after traumatic brain injury in mice.
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Biochemistry and Molecular Biology Laboratory, Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi, India.
Background And Purpose: Traumatic brain injury (TBI) is a complex medical condition affecting people globally. Hydrogen sulfide (HS) is a recently discovered gaseous mediator and is dysregulated in the brain after TBI. Sodium hydrogen sulfide (NaHS), a known donor of HS, is beneficial in various biological processes involving aging and diseases, including injury.
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