Despite the lack of a layered neocortex and fundamental differences in endbrain organization in birds compared with mammals, intelligent species evolved from both vertebrate classes. Among birds, corvids show exceptional cognitive flexibility. Here we explore the neuronal foundation of corvid cognition by recording single-unit activity from an association area known as the nidopallium caudolaterale (NCL) while carrion crows make flexible rule-guided decisions, a hallmark of executive control functions. The most prevalent activity in NCL represents the behavioural rules, while abstracting over sample images and sensory modalities of the rule cues. Rule coding is weaker in error trials, thus predicting the crows' behavioural decisions. This suggests that the abstraction of general principles may be an important function of the NCL, mirroring the function of primate prefrontal cortex. These findings emphasize that intelligence in vertebrates does not necessarily rely on a neocortex but can be realized in endbrain circuitries that developed independently via convergent evolution.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/ncomms3878 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Clinical and genetic description of patients with chronic granulomatous disease in a pediatric hospital.
Biomedica
December 2024
Departamento de Alergología e Inmunología Clínica, Hospital Infantil de México Federico Gómez, Ciudad de México, México.
Introduction: Chronic granulomatous disease is a congenital immune disorder characterized by increased susceptibility to fungal and bacterial infections and dysregulated inflammation. It is caused by defects in the NADPH oxidase and EROS protein.
Objective: To characterize clinically and genetically four patients with chronic granulomatous disease at the Hospital Infantil de México Federico Gómez.
[Clinical case : Prevascular mediastinal mass].
Rev Med Liege
January 2025
Service de Radiodiagnostic, CHU Liège, Belgique.
In the event of a prevascular mediastinal mass, knowledge of the anatomy and content of the mediastinum is an essential prerequisite to establish a differential diagnosis. The «4T» rule is applicable because it is a simple and effective mnemonic. It groups together; thyroid goiter, terrible lymphoma, teratoma and thymoma.
View Article and Find Full Text PDFConversational agents in physical and psychological symptom management: A systematic review of randomized controlled trials.
Int J Nurs Stud
December 2024
School of Nursing, The Hong Kong Polytechnic University, Hong Kong SAR, China.; Research Centre for Chinese Medicine Innovation, The Hong Kong Polytechnic University, Hong Kong SAR, China.; Joint Research Centre for Primary Health Care, The Hong Kong Polytechnic University, Hong Kong SAR, China.. Electronic address:
Background: Effective management of physical and psychological symptoms is a critical component of comprehensive care for both chronic disease patients and apparently healthy individuals experiencing episodic symptoms. Conversational agents, which are dialog systems capable of understanding and generating human language, have emerged as a potential tool to enhance symptom management through interactive support.
Objective: To examine the characteristics and effectiveness of conversational agent-delivered interventions reported in randomized controlled trials (RCTs) in the management of both physical and psychological symptoms.
Leveraging Natural Language Processing and Machine Learning Methods for Adverse Drug Event Detection in Electronic Health/Medical Records: A Scoping Review.
Drug Saf
January 2025
Department of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Background: Natural language processing (NLP) and machine learning (ML) techniques may help harness unstructured free-text electronic health record (EHR) data to detect adverse drug events (ADEs) and thus improve pharmacovigilance. However, evidence of their real-world effectiveness remains unclear.
Objective: To summarise the evidence on the effectiveness of NLP/ML in detecting ADEs from unstructured EHR data and ultimately improve pharmacovigilance in comparison to other data sources.
[Progress on the role of N-end rule pathways in protein degradation].
Sheng Li Xue Bao
December 2024
Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou 325000, China.
The N-end rule pathway is a protein degradation pathway mediated by the ubiquitin-proteasome system, which specifically targets and degrades target proteins by recognizing specific residues at the N-terminus of the proteins. The residues which play a crucial role in the N-end rule pathway are called degrons, also known as N-degrons, as they are usually unstable at the N-terminal end of the protein. Currently, several N-end rule pathways have been identified in the eukaryotes, including the Arg/N-end rule, Ac/N-end rule, and Pro/N-end rule pathways, as well as the recently discovered Gly/N-end rule pathway.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!