An environmentally-friendly, enzyme-promoted procedure for the Henry reaction was first studied using water-in-[Bmim][PF6] microemulsions as reaction medium. The Amano acylase from Aspergillus oryzae showed better catalytic activity for the addition reactions of nitromethane with a series of aromatic aldehydes, and a highest yield of 90% was obtained.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269850 | PMC |
| http://dx.doi.org/10.3390/molecules181113910 | DOI Listing |
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