[Clinical value of CT-guided (125)I brachytherapy for retroperitoneal metastatic lymph node from PHC].

Zhonghua Yi Xue Za Zhi

State Key Laboratory of Oncology in Southern China, Minimally Invasive and Interventional Department, Sun Yat-sen University Cancer Center,Guangzhou 510060, China.

Published: July 2013

AI Article Synopsis

  • The study evaluated the effectiveness of CT-guided (125)I brachytherapy for treating metastatic lymph nodes in patients with primary hepatic carcinoma (PHC).
  • Twenty patients were treated using a computerized treatment planning system to ensure precise placement of radioactive seeds, monitored through CT scans.
  • Results showed a decreasing local control rate over time, with no severe complications reported, indicating that this method is both effective and safe for patients.

Article Abstract

Objective: To discuss the clinical value of CT-guided (125)I brachytherapy with retroperitoneal metastatic lymph nodes from primary hepatic carcinoma(PHC).

Methods: Twenty patients with retroperitoneal metastatic lymph node recurrence from PHC were percutaneously treated by (125)I brachytherapy with computed tomographic (CT) guidance. The number, radioactive dose, placed position of radioactive seeds and puncture path were determined by computerized treatment planning system (TPS). The radioactive seeds were implanted when the needles were in right position by CT scan. Radiotherapy verification and quality assessment were performed after treatment by CT scan. Follow-up contrast material-enhanced CT were reviewed.

Results: The local control rate of 3, 6, 10, 15 months was 70.0%, 56.3%, 44.4%, 25.0% respectively. There were no severe complications such as massive bleeding and radiation injury of normal tissues.

Conclusion: CT-guided (125)I brachytherapy are effective and may be safely applied to retroperitoneal metastatic lymph nodes from PHC.

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