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| http://dx.doi.org/10.3978/j.issn.2223-3652.2013.02.05 | DOI Listing |
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Kounis syndrome following COVID-19 vaccination: Clinical manifestations, mechanisms and management.
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Department of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
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- Kounis syndrome is an acute coronary condition triggered by allergic reactions, resulting in heart damage and, in some cases, anaphylactic shock.
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Department of Allergy, Instituto de Investigación Sanitaria Princesa (IIS-Princesa), Hospital Universitario de La Princesa, Madrid, Spain.
Kounis syndrome (KS) was first described in 1991 by Kounis and Zavras and is also known as allergic angina syndrome or allergy myocardial infarction. It is a rare, and frequently undiagnosed syndrome that is characterized by an anaphylactic reaction. Allergens cause massive degranulation of mast cells leading to coronary spasm, microvascular angina, and/or endothelial dysfunction with myocardial infarction.
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