A rapid, clean, and highly efficient method for synthesis of dihydropyrano[3,2-c]chromene derivatives by one-pot, three-component condensation of aromatic aldehydes, malononitrile, and 4-hydroxycoumarin using DABCO as catalyst in solvent-free neat conditions is described. The present method has the advantages of mild reaction conditions, short reaction times, easy isolation of products, and excellent yields.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824809 | PMC |
| http://dx.doi.org/10.1155/2013/185120 | DOI Listing |
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