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Cross-linking as an adjuvant treatment for tectonic corneal lamellar graft preparation. | LitMetric

AI Article Synopsis

  • The text outlines a new surgical technique for repairing the anterior segment of the eye, specifically targeting issues like scleral and conjunctival melting.
  • The method involves using a pre-cut corneal graft that has undergone cross-linking treatment to address these problems while also serving a dual purpose in endothelial transplantation.
  • Results show that the procedure was successful with no complications, stable visual acuity, and well-functioning grafts one year post-surgery.

Article Abstract

Purpose: To describe a new surgical approach for the tectonic reconstruction of the anterior ocular segment and the management of scleral and conjuctival melting.

Methods: Case series of patients demonstrating anterior segment anomalies, such as scleral and conjunctival melting. The anterior stromal part of a pre-cut corneal graft for Descemet's stripping automated endothelial keratoplasty (DSAEK) was cross-linked with riboflavin and ultraviolet A irradiation and was used to cover scleral (scleral melting in a patient with necrotizing scleritis, one case) and conjuctival (dehiscence of the conjunctiva in patients with anti-glaucomatous valve exposure, two cases) areas. The endothelial part of all corneal grafts was used for DSAEK in patients with need of corneal endothelial transplantation.

Results: Repair of scleral and conjuctival melting was successful in all cases. No intra- or post- operative complications occured. Visual acuity of all patients remained stable during the follow up period. One year postoperatively the corneal graft remained in place and no signs of inflammation were evident, while all grafts were epithelialized.

Conclusions: The use of cross-linked corneal graft for the tectonic reconstruction of the anterior ocular segment represents an adequate surgical approach for the management of scleral and conjuctival melting; while, at the same time it offers the advantage of using one corneal graft for two recipients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837367PMC
http://dx.doi.org/10.2174/1874364101307010079DOI Listing

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