Objective: To present clinicopathologic and immunohistochemical features of 3 cases of rare and unusual condition of urogenital tract, prostatic epithelial polyps situated in various parts of the urinary tract, with a heterogeneous presentation and a benign behavior.
Methods: Detailed data on 3 patients with polyps in the urinary tract presented from January 2008 to December 2012 were reviewed, and the clinicopathologic characteristics of the patients and disease along with various diagnostic and treatment modalities were recorded.
Results: All the 3 patients were aged older than 45 years. The presenting symptom hematuria was common to each patient. One patient had polypoidal growth in preprostatic (intramural) urethra; the other 2 had polyps in bladder. Each patient had other urogenital tract disease, 2 were known case of benign prostatic hyperplasia, and 1 had past history of urinary bladder carcinoma. Clinically, each of the case was misdiagnosed as aggressive lesions; however, after histopathologic diagnosis, management was undertaken according to benign result. No recurrence or metastasis was observed to date. Immunohistochemical stain prostate-specific antigen was positive in the epithelium. All 3 patients were recurrence-free on follow-up.
Conclusion: The prostate type epithelial polyps are rare in urinary bladder and bladder urethra and are frequently associated with concurrent pathologies of urogenital tract. These are benign conditions with differential of other benign and malignant disorders.
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http://dx.doi.org/10.1016/j.urology.2013.10.009 | DOI Listing |
FASEB J
January 2025
Department of Internal Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Serum uric acid is an end-product of purine metabolism. Uric acid concentrations in excess of the physiological range may lead to diseases such as gout, cardiovascular disease, and kidney injury. The kidney includes a variety of cell types with specialized functions such as fluid and electrolyte homeostasis, detoxification, and endocrine functions.
View Article and Find Full Text PDFCureus
December 2024
Department of Medicine, King Faisal Specialist Hospital and Research Center, Jeddah, SAU.
Background Sodium-glucose co-transporter 2 (SGLT2) inhibitors are an emerging treatment for type 2 diabetes mellitus (T2DM). The effect and tolerability of SGLT2 inhibitors in patients with T2DM, especially related risk factors and susceptible populations, are an area of ongoing research. Aim The aim of this study was to evaluate the tolerability of SGLT2 inhibitors, particularly the risk associated with urogenital infection, in patients with T2DM.
View Article and Find Full Text PDFInfect Drug Resist
January 2025
Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Monkeypox (mpox), caused by mpox virus (MPXV) infection, reemerged in 2022 and still raises concerns globally. Abundant clinical data indicate that mpox is a sexually transmitted infection and that the urogenital system is the most frequently involved system in mpox, which deserves more attention. Penile lesions are the most common presentation, followed by urethritis.
View Article and Find Full Text PDFNarra J
December 2024
Department of Tropical Biology, Faculty of Biology, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Dengue hemorrhagic fever (DHF) is a major health concern in tropical and subtropical countries. Indonesia has DHF cases perennially every year. On the other hand, Indonesia is abundant with seaweed ), which can be found across its seashore.
View Article and Find Full Text PDFNarra J
December 2024
Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Endometriosis remains a significant challenge for reproductive-aged women and is frequently associated with infertility. Although in vitro fertilization (IVF) is used to address infertility in women with endometriosis, its effectiveness in this context is still debated, particularly in developing countries such as Indonesia, where IVF remains a major challenge. The aim of this study was to investigate the success rates of early stages of IVF in women with and without endometriosis.
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