Invasive mold infections represent an emerging and important diagnostic challenge, especially in immunocompetent patients when microscopy and cultures of the biological fluids remain negative. A central nervous system localization is not common and the clinical presentation is aspecific.
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http://dx.doi.org/10.1016/j.ijid.2013.10.002 | DOI Listing |
Genetics
January 2025
Dept. of Genetics, Stanford University, Stanford CA 94305-5120, USA.
The Candida Genome Database (CGD; www.candidagenome.org) is unique in being both a model organism database and a fungal pathogen database.
View Article and Find Full Text PDFNat Commun
January 2025
Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Glioblastoma (GBM) is a malignant brain tumor with diffuse infiltration. Here, we demonstrate how GBM cells usurp guidance receptor Plexin-B2 for confined migration through restricted space. Using live-cell imaging to track GBM cells negotiating microchannels, we reveal endocytic vesicle accumulation at cell front and filamentous actin assembly at cell rear in a polarized manner.
View Article and Find Full Text PDFAm J Trop Med Hyg
December 2024
Department of Dermatology, The Second Hospital of Jilin University, Changchun, People's Republic of China.
Mycetoma is a granulomatous disease of subcutaneous tissue that is caused by different species of aerobic filamentous bacteria (actinomycetoma) or fungi (eumycetoma). Mycetoma treatment depends on the causative pathogen, and it mainly consists of antimicrobial interventions or surgery. Aspergillus terreus is an etiologic agent of invasive aspergillosis and a rare cause of eumycetoma that is common in central and southern China.
View Article and Find Full Text PDFRSC Adv
December 2024
Civil and Environmental Engineering Department, University of Perugia Strada di Pentima 4 05100 Terni Italy
The ability of fungi and bacteria to form biofilms on surfaces poses a serious threat to health and a problem in industrial settings. In this work, we investigated how the surface stiffness of silk fibroin (SF) films is modulated by the interaction with black phosphorus (BP) flakes, quantifying the morphogenesis of cells. Raman and infrared (IR) spectroscopies, along with scanning transmission electron microscopy, allowed us to quantify the thickness and diameter of BP flakes dispersed in the SF matrix (, 5.
View Article and Find Full Text PDFMicrobiol Spectr
January 2025
Department of Sciences, John Jay College of the City University of New York, New York, New York, USA.
Unlabelled: The SPFH (stomatin, prohibitin, flotillin, and HflK/HflC) protein superfamily is conserved across all domains of life. Fungal SPFH proteins are required for respiration, stress adaptation, and membrane scaffolding. In the yeast , stomatin-like protein 3 (Slp3) forms punctate foci at the plasma membrane, and overexpression causes cell death following exposure to the surfactant, SDS, and the oxidative stressor, HO.
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