[Pseudotumor phenotype of sarcoidosis: about two cases].

Rev Mal Respir

Service de pneumologie, CHU Hédi-Chaker de Sfax, route el Ain Km1, 3029 Sfax, Tunisie. Electronic address:

Published: November 2013

Introduction: Sarcoidosis is a multisystem benign granulomatous disease of unknown etiology. It can sometimes cause diagnostic confusion by presenting in the form of a pseudotumor, thus constituting a trap for the unwary.

Comments: The authors report two cases of pseudotumor sarcoidosis. In the first, the pseudotumor occurred in the context of multisystem disease in a 48-year-old man. The response to treatment with systemic corticosteroids was complicated by the development of disseminated tuberculosis, which was rapidly fatal. The second case, by contrast, was about a 58-year-old woman and the disease was self-limiting, resolving spontaneously in less than 3 months.

Conclusion: Through these two cases, the authors focus on the particularities of the pseudotumor manifestation of pulmonary sarcoidosis. The diagnosis is often difficult. The mismatch between the clinical picture and the extent of radiological lesions should, however, suggest the diagnosis. Histological evidence is needed to eliminate other etiologies including malignant tumors. The condition usually resolves either spontaneously or after treatment with systemic corticosteroids. However, relapses are possible, including on discontinuation of corticosteroid therapy.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rmr.2013.04.017DOI Listing

Publication Analysis

Top Keywords

treatment systemic
8
systemic corticosteroids
8
[pseudotumor phenotype
4
sarcoidosis
4
phenotype sarcoidosis
4
sarcoidosis cases]
4
cases] introduction
4
introduction sarcoidosis
4
sarcoidosis multisystem
4
multisystem benign
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!