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Enhancement to effusion: Breast implant-associated anaplastic large cell lymphoma.
J Cardiol Cases
December 2024
Department of Internal Medicine, University of Texas at Austin Dell Medical School, Austin, TX, USA.
Unlabelled: This case is a rare presentation of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), where malignant pericardial effusion (MPE) served as the primary manifestation. A 58-year-old woman, post-breast implant removal, presented with pleuritic chest pain, fever, and chills. Clinical evaluation revealed jugular venous distention, muffled heart sounds, and hemodynamic instability.
View Article and Find Full Text PDFEmerging Non-Breast Implant-Associated Lymphomas: A Systematic Review.
Cancers (Basel)
December 2024
PROMISE Department, University of Palermo, 90127 Palermo, Italy.
Medical devices used for functional or esthetic purposes improve health and quality of life; however, they are not risk-free. Anaplastic large-cell lymphoma (ALCL), associated with breast implants, is a well-known and recognized distinct lymphoma entity. More recently, additional lymphomas have been reported in relation to prosthesis other than breast implants, as these allow the pericyte to develop into a clone that undergoes a maturation process, progressing toward full malignancy.
View Article and Find Full Text PDFA positionally stable anatomic smooth breast implant.
Biomed Mater
December 2024
Laboratory of Bioregenerative Medicine & Surgery, Department of Surgery, Division of Plastic Surgery, Weill Cornell Medical College, New York, NY, United States of America.
The voluntary recall of textured breast implants due to their association with breast implant-associated anaplastic large cell lymphoma has resulted in the loss of the primary advantage of the textured surface: positional stability. We have engineered a novel soft gel-filled smooth implant with a surface that promotes positional stability without texture, known as the positionally stable smooth implant (PSSI). Miniature anatomically shaped breast implant shells were fabricated from polydimethylsiloxane using 3D-printed molds.
View Article and Find Full Text PDFSingle-cell Sequencing of Circulating Human Plasmablasts during Staphylococcus aureus Bacteremia.
J Immunol
December 2024
Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
Article Synopsis
- Staphylococcus aureus is a leading cause of severe healthcare-related infections, and existing antibiotic treatments often have high mortality rates, necessitating new treatment approaches.
- Researchers studied blood samples from 17 S. aureus bacteremia patients to analyze immune responses by isolating plasmablasts and sequencing their antibody genes, resulting in the identification of over 300 unique antibody sequences.
- Four novel monoclonal antibodies (mAbs) were developed, with one specifically targeting wall teichoic acid in S. aureus, while three showed cross-reactivity with Staphylococcus epidermidis and were able to trigger immune cell phagocytosis of staphylococci.
Smooth Operator: Nanotextured Breast Tissue Expanders Are Associated with Lower Rates of Capsular Contracture.
J Clin Med
September 2024
Department of Plastic, Reconstructive and Aesthetic Surgery and Hand Surgery, Centre Hospitalier Universitaire Vaudois (CHUV), CH-1011 Lausanne, Switzerland.
Continuous research on breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) has introduced a focus on surface texturizations and a shift towards smooth breast devices, yet outcomes comparing the complication profiles of differently textured tissue expanders (TEs) remain conflicting. The study aim was to compare the complication profile of a new nanotextured and MRI-compatible TE to micro- and macrotextured TEs and to identify possible predictors for complications. A retrospective analysis of women undergoing expander-based breast reconstruction after mastectomy between January 2016 and March 2022 was conducted.
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