Emerging biomedicines based on bacteriophages.

Crit Rev Eukaryot Gene Expr

Institute of Modern Biopharmaceuticals, State Key Laboratory Breeding Base of Eco-Environment and Bio-Resource of the Three Gorges Area, School of Life Sciences, Southwest University, Beibei, Chongqing 400715, China.

Published: June 2014

AI Article Synopsis

  • Bacteriophage is a common bacterial virus that exists widely in nature.
  • Researchers are exploring bacteriophages and their proteins, like endolysin and holin, as potential new therapies to combat antibiotic resistance.
  • Additionally, engineered bacteriophages show potential for innovative drug delivery systems and diagnostic methods.

Article Abstract

Bacteriophage is bacterial virus widespread in the biosphere. Bacteriophages and their encoded endolysin (or lysin), holin, and other small proteins are intensively pursed as novel therapeutic agents to complement and tackle the increasing antibiotics resistance. Moreover, the delivery system based on bacteriophage and the diagnostic method based on engineered bacteriophage were also promising new avenues to drug delivery and diagnosis.

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Source
http://dx.doi.org/10.1615/critreveukaryotgeneexpr.2013006578DOI Listing

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