Introduction: IM nails have gained popularity for stabilization of humeral shaft fractures (HSF). The initial enthusiasm was tempered by a number of specific complications and thus indications need to be re-evaluated.
Patients And Methods: This retrospective study includes 111 patients with HSF subjected to a treatment protocol of IM fixation with first and second generation of humeral nails. Antegrade approach was used in 105 (94.5%) and retrograde in 6 (5.5%) patients. Reaming was performed in 51 (45.9%) fractures. The study covers a period of 10 years. Mean follow-up time was 3.5 (1-6) years. This investigation is directed at technical errors and complications, especially those corrected by secondary surgery.
Results: We registered 52 (46.85%) intra-operative complications in 40 (36.04%) patients, on average 1.3 per patient. The most common were: distraction n=5 (4.5%), long proximal locking screws n=9 (8.1%), additional diaphyseal fracture n=7 (6.3%) and countersinking of the nail in the humeral head n=8 (7.2%). The number of postoperative complications was 40 (36.0%) related to 19 (17.1%) patients. Technical errors, such as distraction, longer nail and additional fractures have affected time to union and resulted in chronic shoulder pain. 36 (32.5%) secondary surgeries were needed to address these problems. When first generation nails are used, the intra-operative complication related risk increases 1.58 times, and the postoperative complication related risk is 1.67 times higher compared to second generation nails. According to Constant-Murley score excellent and very good functional results were achieved in 93 (83.78%) patients. While reaming did not influence the clinical results for both nail generations, overall better results were achieved with second generation nails. Postoperative shoulder pain has been registered in 18 (16.2%) patients.
Conclusion: We registered a number of technical errors and complications, which we consider technique specific. The analysis and avoidance of these complications, related only to IM nailing of the humerus, will allow IM nails to successfully bridge the gap between functional bracing and plating.
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http://dx.doi.org/10.1016/j.injury.2013.10.044 | DOI Listing |
Chaos
January 2025
Centre for Complex Systems, School of Mathematical Sciences, Queen Mary University of London, Mile End Road, London E1 4NS, United Kingdom.
Since groundbreaking works in the 1980s it is well-known that simple deterministic dynamical systems can display intermittent dynamics and weak chaos leading to anomalous diffusion. A paradigmatic example is the Pomeau-Manneville (PM) map which, suitably lifted onto the whole real line, was shown to generate superdiffusion that can be reproduced by stochastic Lévy walks (LWs). Here, we report that this matching only holds for parameter values of the PM map that are of Lebesgue measure zero in its two-dimensional parameter space.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
February 2025
Cultural Heritage Unit, Conservation Services Division, South African National Parks, Pretoria 0002, South Africa.
The rise and spread of ancient Indian Ocean Rim (IOR) trade networks profoundly impacted southern Africa. Control over this trade played a critical role in the rise and maintenance of complex societies of the second millennium CE such as Mapungubwe and Great Zimbabwe. While the African origins of this trade lie in the first millennium CE, understanding its earliest phases and subsequent development in the far south has been hampered by a general paucity of research.
View Article and Find Full Text PDFJ Fam Psychol
January 2025
Department of Psychology and Neuroscience, Baylor University.
Parental monitoring is a robust family-level predictor of youth well-being. Identification of variations by gender and/or race/ethnicity in parental monitoring has important implications for tailoring parenting practices. However, valid comparisons can only be conducted if cross-subpopulation measurement equivalence is established.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Rheumatology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, P.R. China.
Introduction: Lupus nephritis (LN) is one of the most frequent and serious organic manifestations of systemic lupus erythematosus (SLE). Autophagy, a new form of programmed cell death, has been implicated in a variety of renal diseases, but the relationship between autophagy and LN remains unelucidated.
Methods: We analyzed differentially expressed genes (DEGs) in kidney tissues from 14 LN patients and 7 normal controls using the GSE112943 dataset.
PLoS One
January 2025
Department of Anatomy, University Hospital Essen, Essen, Germany.
Prostate cancer is the second most common type of cancer in male worldwide. Stromal-epithelial interaction is thought to have a major impact on cancer development and progression. Previous studies have shown that interaction via soluble factors lead to a reduction in the expression of xCT and AL122023.
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