The use of susceptibility-weighted imaging for epileptic focus localization in acute-stage pediatric encephalopathy: a case report.

Pediatr Neurol

Department of Pediatrics, Tokyo Metropolitan Hiroo General Hospital, Japan; Department of Pediatrics and Child Health, Nihon University School of Medicine, Japan.

Published: February 2014

AI Article Synopsis

  • Susceptibility-weighted imaging is a new MRI technique that detects the paramagnetic properties of blood, helping identify issues in the brain.
  • In this study, three children with severe seizures due to fever were evaluated, and the imaging revealed notable changes in their brain's venous blood vessels related to their seizures.
  • Unlike traditional MRI methods, which showed no problems, susceptibility-weighted imaging provided important insights that confirmed the locations of the seizures, and all patients recovered fully without lasting effects.

Article Abstract

Background: Susceptibility-weighted imaging is a novel high-spatial-resolution three-dimensional gradient-echo magnetic resonance imaging technique with phase postprocessing that accentuates the paramagnetic properties of blood products. The use of susceptibility-weighted imaging for epileptic focus localization in the acute stage of encephalopathy in a child has not been documented.

Patients: We report three pediatric patients with status epilepticus in the setting of fever, in whom susceptibility-weighted imaging showed transient prominence of the focal venous vasculature.

Results: Conventional cranial T1- and T2-weighted images and diffusion-weighted images showed no abnormalities. The prominence of the focal venous vasculature in these patients, as demonstrated by susceptibility-weighted imaging, was consistent with the epileptic focuses suggested by both clinical symptoms and electroencephalograph findings and resolved completely without neurological sequelae in all patients.

Conclusions: Susceptibility-weighted imaging may facilitate assessing epileptic focus localization in the acute stage of encephalopathy in children.

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Source
http://dx.doi.org/10.1016/j.pediatrneurol.2013.09.004DOI Listing

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