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Factors associated with onset-to-door time in patients with transient ischemic attack admitted to stroke centers. | LitMetric

Factors associated with onset-to-door time in patients with transient ischemic attack admitted to stroke centers.

Stroke

From the Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan (T.U., K.M.); Department of Stroke Medicine, Kawasaki Medical School, Kurashiki, Japan (K.K.); Department of Cerebrovascular Medicine and Neurology, Clinical Research Institute, National Hospital Organization Kyushu Medical Center, Fukuoka, Japan (Y.O.); Department of Neurology, Nagoya Daini Red Cross Hospital, Nagoya, Japan (Y.H.); Department of Neurology and Cerebrovascular Medicine, Saitama Medical University Saitama International Medical Center, Hidaka, Japan (N.T.); Department of Stroke Science, Research Institute for Brain and Blood Vessels-Akita, Akita, Japan (A.S); Department of Neurology, Tokai University, Isehara, Japan (S.T.); Department of Neurosurgery, Nakamura Memorial Hospital, Sapporo, Japan (J.N.); Department of Neurology, Ebara Hospital, Tokyo, Japan (K.A.); Department of Neurosurgery, Tokushima University, Tokushima, Japan (S.N.); Department of Neurosurgery, Iwate Medical University, Morioka, Japan (K.O); Department of Neurology, Tokyo Women's Medical University, Tokyo, Japan (T.N., S.U.); Department of Clinical Neuroscience and Therapeutics, Hiroshima University, Hiroshima, Japan (M.M.); and Department of Neurosurgery, National Cerebral and Cardiovascular Center, Suita, Japan (K.I.).

Published: February 2014

AI Article Synopsis

Article Abstract

Background And Purpose: The aim of this study was to elucidate the factors associated with the time from symptom onset to arrival at a stroke center (onset-to-door time [ODT]) in patients with classically defined transient ischemic attack using data from a multicenter, retrospective study.

Methods: The subjects were patients with transient ischemic attack admitted to 13 stroke centers in Japan within 7 days of onset between 2008 and 2009. A total of 464 patients registered (292 men, 68.5±13.2 years old), and 421 of them (268 men, 68.8±13.1 years old) were included in the analyses. ODT was classified into the following 5 categories: <3 hours, 3 to 6 hours, 7 to 12 hours, 13 to 24 hours, and >24 hours.

Results: There were 233 patients (55.3%) who visited a stroke center within 3 hours of symptom onset. Multiple ordinal logistic regression analysis revealed that motor weakness, speech disturbance, and duration of symptoms >10 minutes were independently associated with a short ODT. Furthermore, a history of transient ischemic attack and hypertension and a referral from another medical facility were independently associated with a long ODT. Patients with a higher ABCD2 score were likely to arrive at a stroke center more quickly.

Conclusions: We identified several factors that were positively and negatively associated with the ODT in patients with transient ischemic attack.

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Source
http://dx.doi.org/10.1161/STROKEAHA.113.003367DOI Listing

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