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Factors associated with treatment response in chronic nonbacterial osteomyelitis at a single center: a retrospective cohort study.
Pediatr Rheumatol Online J
January 2025
Division of Pediatric Rheumatology, Seattle Children's Hospital, 4800 Sand Point Way NE, Seattle, WA, 98105, USA.
Background: NSAIDs are commonly used as first line therapy in chronic nonbacterial osteomyelitis (CNO) but are not effective for all patients. The objective of this study was to identify clinical variables associated with NSAID monotherapy response versus requiring second-line medication in a single-center cohort of patients with CNO.
Methods: The charts of children with CNO who attended a CNO clinic at a quaternary care center between 1/1/05 and 7/31/21 were retrospectively reviewed.
Spontaneously regressing mass-like soft tissue involvement in a child with chronic non-bacterial osteomyelitis: case-based review.
Rheumatol Int
January 2025
Department of Pediatric Rheumatology, Istanbul Medeniyet University, Istanbul, Turkey.
Chronic non-bacterial osteomyelitis (CNO) is an inflammatory bone disease, usually diagnosed in childhood. It is characterized by the presence of multifocal or unifocal osteolytic lesions that can cause bone pain and soft tissue swelling. CNO is known to have soft tissue involvement.
View Article and Find Full Text PDFDevelopment and validation of a prognostic nomogram model for severe osteomyelitis patients.
Sci Rep
January 2025
Department of Pediatric Surgery, Women and Children's Hospital Affiliated to Ningbo University, No. 339 Liuting Street, Ningbo, 315012, Zhejiang Province, China.
After severe infection in osteomyelitis patients in the Intensive Care Unit (ICU), there's a higher risk of mortality. However, limited research exists on predicting prognosis. Develop a predictive model for 1-year mortality risk in ICU-admitted osteomyelitis patients to inform clinical diagnosis and treatment.
View Article and Find Full Text PDFAssociation between red blood cell distribution width and mortality in severe osteomyelitis patients.
Sci Rep
January 2025
Department of Pediatric Surgery, Women and Children's Hospital Affiliated to Ningbo University, No. 339 Liuting Street, Ningbo, 315012, Zhejiang, China.
Red blood cell distribution width (RDW) is considered to be associated with the prognosis of patients with severe infections. This study aims to investigate the relationship between RDW and prognosis in osteomyelitis patients admitted to the ICU. Through a retrospective cohort study, relevant records of severe osteomyelitis patients were collected from the Medical Information Mart for Intensive Care (MIMIC-IV) database.
View Article and Find Full Text PDFPlain radiographs can still be of considerable diagnostic value for recognizing Brodie's abscess, especially in resource constrained settings.
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