An enantioselective intramolecular O-arylation was achieved through desymmetrization with Pd-catalyzed coupling reactions. The intramolecular asymmetric aryl C-O coupling reactions of 2-(2-haloaryl)propane-1,3-diols led to the enantioselective formation of chiral (3,4-dihydro-2H-chromen-3-yl)methanols in good yields and high enantiomeric selectivity.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/ol402911y | DOI Listing |
Publication Analysis
Top Keywords
intramolecular o-arylation
8
coupling reactions
8
pd-catalyzed desymmetric
4
desymmetric intramolecular
4
o-arylation reaction
4
reaction enantioselective
4
enantioselective synthesis
4
synthesis 34-dihydro-2h-chromen-3-ylmethanols
4
34-dihydro-2h-chromen-3-ylmethanols enantioselective
4
enantioselective intramolecular
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!