The function of each organ including the brain tends to decline with aging. This influences on the appearance of psychotic symptoms in the elderly. A manic state in the elderly is often atypical and different from that in younger and middle aged patients. Manic pseudodementia is an important symptom, which means that elderly manic patients easily show dementia-like behavior because of their Tatendrang(pressured action) or hyperkinesis, so they are misdiagnosed as having dementia. On medication, as the response to drugs is different to that in younger patients, side effects easily appear in the elderly. However, we have very few clinical-pharmacological data on the use of major tranquilizers including anti-manic drugs for elderly patients.
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