The multi-disciplinary French project "Adaptation à la Fiévre de la Vallée du Rift" (AdaptFVR) has concluded a 10-year constructive interaction between many scientists/partners involved with the Rift Valley fever (RVF) dynamics in Senegal. The three targeted objectives reached were (i) to produce--in near real-time--validated risk maps for parked livestock exposed to RVF mosquitoes/vectors bites; (ii) to assess the impacts on RVF vectors from climate variability at different time-scales including climate change; and (iii) to isolate processes improving local livestock management and animal health. Based on these results, concrete, pro-active adaptive actions were taken on site, which led to the establishment of a RVF early warning system (RVFews). Bulletins were released in a timely fashion during the project, tested and validated in close collaboration with the local populations, i.e. the primary users. Among the strategic, adaptive methods developed, conducted and evaluated in terms of cost/benefit analyses are the larvicide campaigns and the coupled bio-mathematical (hydrological and entomological) model technologies, which are being transferred to the staff of the "Centre de Suivi Ecologique" (CSE) in Dakar during 2013. Based on the results from the AdaptFVR project, other projects with similar conceptual and modelling approaches are currently being implemented, e.g. for urban and rural malaria and dengue in the French Antilles.
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http://dx.doi.org/10.4081/gh.2013.73 | DOI Listing |
PLoS One
January 2025
Department of Disease Control, School of Veterinary, Medicine, University of Zambia Lusaka, Lusaka, Zambia.
Rift Valley fever (RVF) is an important viral zoonotic disease that not only affects ruminants but causes serious morbidity and mortality in humans. In humans, its symptoms range from mild flu-like signs to a severe form such as retinal damage, meningoencephalitis to haemorrhagic fever. In this study, 202 human serum samples were collected from central and western parts of Zambia and tested for RVF-specific antibodies using a commercially available ELISA kit.
View Article and Find Full Text PDFMol Ther Methods Clin Dev
March 2025
Beijing Institute of Tropical Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing Key Laboratory for Research on Prevention and Treatment of Tropical Diseases, Beijing, China.
In recent years, mRNA vaccines have emerged as a leading technology for preventing infectious diseases due to their rapid development and high immunogenicity. These vaccines encode viral antigens, which are translated into antigenic proteins within host cells, inducing both humoral and cellular immune responses. This review systematically examines the progress in mRNA vaccine research for major mosquito-borne viruses, including dengue virus, Zika virus, Japanese encephalitis virus, Chikungunya virus, yellow fever virus, Rift Valley fever virus, and Venezuelan equine encephalitis virus.
View Article and Find Full Text PDFVet Ital
January 2025
University Hospital College, University of Ibadan, Nigeria.
The advancement of small ruminant farming in Benin has encountered challenges associated with health issues and agricultural practices. This study aimed to provide the initial documentation of the prevalence of enzootic ovine abortion and evaluate the health status of animals concerning various recurring diseases on traditional small ruminant farms in Benin. In 2023, a semi-structured survey of 450 farms was carried out in two agricultural development centers in Benin.
View Article and Find Full Text PDFEur J Public Health
January 2025
Federal Ministry of Health, Directorate Health Emergencies and Epidemics Control (HEEC), Khartoum, Sudan.
Rift Valley Fever is endemic in Sudan, with a notable outbreak declared in 2019, affecting multiple states. In this study, we examine the Red Sea State, Sudan's experience in applying the One Health approach, to contain Red-Sea RVF outbreak. A retrospective analysis of national and sub-national data and a review of literature were conducted to assess the application of One Health response and to derive lessons learned.
View Article and Find Full Text PDFEur J Public Health
January 2025
Department of Community Health, Amref International University, Nairobi, Kenya.
The Chikungunya virus (CHIKV) presents substantial public health challenges in the Eastern Mediterranean Region (EMR), with its prevalence and interaction with other arboviruses (ABVs) remaining poorly understood. This systematic review and meta-analysis aimed to assess the prevalence of CHIKV and its association with other ABVs, such as dengue virus (DENV), Rift Valley fever virus (RVFV), malaria, and yellow fever virus (YFV), in the EMR. We systematically searched databases including PubMed, Embase, Web of Science, Scopus, Cochrane Library, CINAHL, PsycINFO, and ScienceDirect to identify epidemiological studies that report CHIKV prevalence and provide odds ratios (ORs) for CHIKV compared to other ABVs.
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