Background: High rejection rates of subject recruitments for research studies have been reported in immigrants in many countries. However, the barriers in recruiting members of the expatriate population in Kuwait have not yet been investigated. This study was therefore designed to identify barriers in recruiting expatriates for research studies in the state of Kuwait.
Methods: A population-based cross-sectional study was conducted on expatriate subject's aged 18 years and older living in Kuwait. Difference between groups of continuous independent variables was analyzed using the t-test. Different categories such as ethnicity and gender were compared using the chi-square test.
Results: 3460 (85.1%) participants were recruited and 617 (14.2%) refused to participate in the study while 2530 (38%) calls were unreachable from the total of 6607 calls placed. Younger subjects (mean age 41.1 years) were more hesitant to be part of the study compared to older participants. The rejections among South Asians was (41.8%), Arabs (32.6%), Southeast Asians (18.9%) while the others (6.6%) category was least to refuse among all the nationalities. Gender was not significantly associated with refusal.
Conclusion: There is an acute lack of appropriate recording of the problems faced while recruiting the participants. The findings suggest important messages for the decision makers in the area of expatriate recruitments, to understand the challenge and design new strategies to overcome the problem of recruitment in the state of Kuwait for research studies.
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http://dx.doi.org/10.1186/1475-9276-12-93 | DOI Listing |
Eur Heart J
January 2025
Department of Primary Care and Public Health, Imperial Centre for Cardiovascular Disease Prevention, School of Public Health, Imperial College London, White City Campus, 90 Wood Lane, London W12 0BZ, UK.
Background And Aims: Overweight and obesity are modifiable risk factors for atherosclerotic cardiovascular disease (ASCVD) in the general population, but their prevalence in individuals with heterozygous familial hypercholesterolaemia (HeFH) and whether they confer additional risk of ASCVD independent of LDL cholesterol (LDL-C) remains unclear.
Methods: Cross-sectional analysis was conducted in 35 540 patients with HeFH across 50 countries, in the EAS FH Studies Collaboration registry. Prevalence of World Health Organization-defined body mass index categories was investigated in adults (n = 29 265) and children/adolescents (n = 6275); and their association with prevalent ASCVD.
J Infect Public Health
December 2024
Department of Pharmaceutical Sciences, College of Pharmacy, QU Health, Qatar University, P.O. Box 2713, Doha, Qatar. Electronic address:
Sci Immunol
January 2025
Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Human recombination-activating gene (RAG) deficiency can manifest with distinct clinical and immunological phenotypes. By applying a multiomics approach to a large group of -mutated patients, we aimed at characterizing the immunopathology associated with each phenotype. Although defective T and B cell development is common to all phenotypes, patients with hypomorphic variants can generate T and B cells with signatures of immune dysregulation and produce autoantibodies to a broad range of self-antigens, including type I interferons.
View Article and Find Full Text PDFAm J Ther
January 2025
Al-Manara CAP Centre, Kuwait Centre for Mental Health (KCMH), Shuwaikh, State of Kuwait.
Low Urin Tract Symptoms
January 2025
Farwaniya Hospital, Farwaniya, Kuwait.
Objectives: During holmium laser enucleation of the prostate (HOLEP), blunt dissection (BD) by pushing the tip of the scope may exert mechanical force on the sphincter that could be avoided by adopting laser dissection (LD). This study evaluates the continence recovery in consecutive patients who underwent BD and LD.
Methods: A prospective cohort of patients who underwent LD was compared with a retrospective control that underwent BD.
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