Rheumatoid arthritis (RA) is a heterogeneous disease. In rheumatology, researchers have not identified useful clinical markers to predict the effects of biological agents or of nonbiological, antirheumatic drugs before administration. Since the advent of biological agents, therapeutic strategies for RA have focused on early detection and early intensive treatment. Although responders to Japanese Oriental (Kampo) medicine exist, physicians first have had to diagnose RA using the practices of conventional medicine. They could identify those patients who would benefit from administration of Kampo medicine only by administering the treatment. Only the presence of a positive response could confirm the benefits for a particular individual. In this article, the author discusses the clinical importance of Kampo medicine within the context of the present RA classification criteria and therapeutic treatment and discusses the use of the basal value of anti-CCP antibody (aCCP) titer as a prognostic factor for use of Kampo medicine for RA. The author then defines a methodology for determining who should receive the treatment.
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Front Oncol
December 2024
Clinic for Gastroenterology and Gastrointestinal Oncology, University Medical Center Göttingen (UMG), Göttingen, Germany.
Pancreatic ductal adenocarcinoma (PDAC) is characterized by its poor prognosis. Traditional Japanese herbal medicine (Kampo), such as Juzentaihoto (a standardized combination of 10 herbal extracts), has shown immune modulatory effects, modulation of microcirculation, and amelioration of fatigue. It is administered to patients to prevent deterioration of cachexia and counteract side effects of chemotherapy.
View Article and Find Full Text PDFSurg Today
December 2024
Division of Thoracic Surgery, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuou-ku, Kobe, Hyogo, 650-0017, Japan.
Purpose: This study evaluated the efficacy of ninjin'yoeito for alleviating postoperative symptoms after lung cancer surgery.
Methods: Overall, 140 patients who underwent lobectomy were randomized into a conventional treatment group and a ninjin'yoeito group. The primary endpoint was change in the Cancer Fatigue Scale (CFS) score from baseline and the secondary endpoints were the Cancer Dyspnea Scale (CDS) scores, the Kihon Checklist, and respiratory function.
Cureus
November 2024
Department of Integrative Physiology, Akita University Graduate School of Medicine, Akita, JPN.
The global incidence of mortality due to heart failure (HF) is on the rise, presenting a significant challenge in various regions, including Japan. There is an urgent need for innovative prevention and treatment strategies to address this issue. Traditional medicine, particularly Japanese Kampo medicine (JKM), has been proposed as a potential therapeutic approach and has undergone examination in clinical trials related to HF.
View Article and Find Full Text PDFFront Med (Lausanne)
December 2024
National Key Laboratory of Plant Molecular Genetics, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China.
Medicinal plants, also known as herbs, have been discovered and utilized in traditional medical practice since prehistoric times. Medicinal plants have been proven rich in thousands of natural products that hold great potential for the development of new drugs. Previously, we reviewed the types of Chinese traditional medicines that a Tang Dynasty monk Jianzhen (Japanese: Ganjin) brought to Japan from China in 742.
View Article and Find Full Text PDFPediatr Neonatol
December 2024
Department of Pediatric Surgery, Graduate School of Medicine, The University of Tokyo, Japan. Electronic address:
Background: The treatments and outcomes of pediatric gastroduodenal perforations have rarely been described.
Methods: We retrospectively identified 515 patients aged 28 days to 17 years who were hospitalized for gastroduodenal perforation between July 2010 and March 2021 using a nationwide inpatient database. We compared characteristics, treatments, and outcomes for pediatric gastroduodenal perforation between children aged <7 years (n = 38) and ≥7 years (n = 477).
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