Pseudothrombocytopenia secondary to ethylenediaminetetra-acetic acid induced platelet aggregation observed in a healthy perioperative male patient is reported in order to create awareness among anesthesiologist and laboratory personnel. The mechanisms for such changes have been highlighted.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819855 | PMC |
http://dx.doi.org/10.4103/0970-9185.119152 | DOI Listing |
Cureus
August 2022
Intensive Care Unit, Kawaguchi Cardiovascular and Respiratory Hospital, Kawaguchi, JPN.
Pseudothrombocytopenia (PTCP) is a phenomenon in which platelet aggregation occurs in vitro when an anticoagulant such as ethylenediaminetetraacetic acid (EDTA) is used in a blood sample, causing automated cell counters (ACC) to calculate a lower platelet count than the actual count. While a peripheral blood smear is required to assess platelet count in PTCP accurately, such a time-consuming test is not accessible during the perioperative period. In this study, we evaluated platelet function using thromboelastography (TEG) for a patient with PTCP requiring cardiac reoperation.
View Article and Find Full Text PDFJ Anesth
August 2016
Department of Anesthesiology, Hirosaki University Graduate School of Medicine, 5 Zaifucho, Hirosaki, 036-8562, Japan.
We experienced an unexpected thrombocytopenia detected only in vitro during radical prostatectomy for a 66-year-old patient. Thrombocytopenia with platelet aggregation was observed in a blood sample obtained using a heparinized syringe (not by ethylene diamine tetra-acetic acid tube). Although we could not exclude platelet agglutination in vivo, no thrombosis or coagulation disorder was observed.
View Article and Find Full Text PDFJ Anaesthesiol Clin Pharmacol
October 2013
Department of Emergency and Critical Care Medicine, Sri Gokulam Hospitals and Research Institute, Salem, India.
Pseudothrombocytopenia secondary to ethylenediaminetetra-acetic acid induced platelet aggregation observed in a healthy perioperative male patient is reported in order to create awareness among anesthesiologist and laboratory personnel. The mechanisms for such changes have been highlighted.
View Article and Find Full Text PDFMasui
October 2003
Department of Anesthesiology, National Cancer Center East Hospital, Chiba 277-0882.
A 74-year-old male was operated for sigmoid colon cancer. Because of an agglutination of the patient's platelet, it was difficult to measure his platelet count under ethylene diamine tetra acetate (EDTA), heparin or citrate as anticoagulants with an automated cell counter. Even though there was a strong possibility of pseudothrombocytopenia, anesthetic management for the patient was safely conducted.
View Article and Find Full Text PDFBr J Anaesth
May 2000
Department of Anaesthesia, Royal Free Hampstead NHS Trust, London, UK.
A 73-yr-old man with severe ischaemic heart disease presented for coronary artery bypass grafting. His preoperative platelet count, obtained from an ethylene diamine tetraacetic acid (EDTA) sampling bottle, was 61 x 10(9) litre-1, but he had no history of bleeding problems. Previous platelet counts demonstrated results ranging from 16 x 10(9) litre-1 to 254 x 10(9) litre-1 with variable degrees of in vitro platelet clumping.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!