Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/rheumatology/ket340 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Probable IgG4-related Orbital Disease Masked by Exuberant Ocular Surface Pseudoepitheliomatous Hyperplasia.
Ophthalmic Plast Reconstr Surg
January 2025
The Operation Eyesight Universal Institute for Eye Cancer, Ophthalmic Pathology Laboratory, LV Prasad Eye Institute, Hyderabad, India.
A 40-year-old woman presented with a mass in her OS for 2 years. Examination revealed a large conjunctival lesion on the nasal bulbar conjunctiva OS and a small upper tarsal conjunctival lesion in the OD. Biopsy OD revealed inflammatory granulation tissue, and OS revealed pseudoepitheliomatous hyperplasia with granulation tissue.
View Article and Find Full Text PDFTear inflammatory cytokine profiles in orbital inflammatory disease.
Exp Eye Res
December 2024
Department of Ophthalmology, The Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Tear inflammatory cytokines are a novel biomarker studied in a range of ocular surface diseases, periorbital and orbital conditions. This single-centre prospective study between 2022 and 2024 aims to characterise tear cytokine profiles (Interleukin-1β [IL-1β], IL-2, IL-6, Interferon-γ [IFN-γ] and Tumour Necrosis Factor-α [TNF- α]) in orbital inflammatory disease (OID). OID patients had pre-treatment tear collection via micropipette, and cytokine analysis via multiplex bead array analysis.
View Article and Find Full Text PDFIgG4-related disease for the hematologist.
Hematology Am Soc Hematol Educ Program
December 2024
Division of Hematology, University of British Columbia, Vancouver, British Columbia, Canada; and Division of Hematology, Dalhousie University, Halifax, Nova Scotia, Canada.
Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated disease with many important manifestations in hematopoietic and lymphoid tissue. IgG4 is the least naturally abundant IgG subclass, and the hallmark feature of IgG4-RD is markedly increased IgG4-positive plasma cells (with an IgG4 to IgG ratio >40%) in affected tissue, along with elevated polyclonal serum IgG and IgG4 in most patients. Histological diagnosis is essential, and other key features include storiform fibrosis, lymphoplasmacytic infiltrate, tissue eosinophilia, and obliterative phlebitis.
View Article and Find Full Text PDFPlasma cell type Castleman's disease of lacrimal gland: a case report and literature review.
BMC Ophthalmol
November 2024
Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
Background: Orbital Castleman's disease is a rare benign lymphoproliferative disorder of extranodal origin.
Case Presentation: A 72-year-old man presented with bilateral upper eyelid swelling. Radiology revealed enlarged lacrimal glands in both eyes.
Comparison between Immunoglobulin G4-Related Eye Disease and Other Entities with Non-Immunoglobulin G4 Ocular Involvement.
Eur J Rheumatol
July 2024
Department of Rheumatology, Hospital J.M. Cullen, Santa Fe, Argentina.
Article Synopsis
- The study aimed to differentiate IgG4-related ocular disease (IgG4-ROD) from non-IgG4 ocular diseases by examining various clinical and analytical features.
- It involved 18 patients with IgG4-ROD and 12 with other inflammatory or autoimmune conditions, comparing demographic profiles and symptoms like proptosis and diplopia.
- Results showed a higher prevalence of specific symptoms like proptosis and xerophthalmia in IgG4-ROD, with significant associations found between certain features and the disease type.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!