Background: Nephrotic syndrome (NS) is characterized by water and sodium retention, which leads to edema. The non-osmotic stimulation of arginine vasopressin release from the pituitary gland has been implicated as one of the important factors in abnormal water retention in patients with NS.
Case-diagnosis/treatment: We present the initial description of a patient with massive edema caused by refractory nephrotic syndrome, which was effectively treated with tolvaptan, a selective oral vasopressin V2 receptor antagonist.
Conclusions: Tolvaptan is effective for the treatment of massive edema caused by NS. Larger studies are needed in the future to fully assess the value and safety of tolvaptan use for this condition.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00467-013-2687-1 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Rapunzel syndrome leading to acute intestinal obstruction in a teenager: A rare case report.
Int J Surg Case Rep
December 2024
King Edward Medical University, Lahore 54000, Punjab, Pakistan.
Introduction And Importance: Trichobezor is a mass of accumulated ingested hair in the gastric lumen. Rapunzel syndrome is an extension of these bezoars beyond the pylorus. The formation of trichobezoar is invariably linked to trichotillomania and trichophagia.
View Article and Find Full Text PDFDiagnosis and management challenges of recurrent lupus pericarditis in pregnancy: A case report.
Case Rep Womens Health
December 2024
Department of Obstetrics and Gynecology, Faculty of Medicine, Airlangga University, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Systemic lupus erythematosus (SLE) is an autoimmune multisystem disease. Pericarditis in SLE can lead to severe effusion and cardiac tamponade, and is associated with significant morbidity and mortality. Therefore, early diagnosis and treatment are essential.
View Article and Find Full Text PDFBioactive hydrogel synergizes neuroprotection, macrophage polarization, and angiogenesis to improve repair of traumatic brain injury.
Mater Today Bio
December 2024
Key Laboratory of Biomaterials of Guangdong Higher Education Institutes, Key Laboratory of Regenerative Medicine of Ministry of Education, Guangdong Provincial Engineering and Technological Research Centre for Drug Carrier Development, Department of Biomedical Engineering, Jinan University, Guangzhou, 510632, China.
Article Synopsis
- Traumatic brain injury (TBI) can result in serious cognitive decline and even death due to massive neuronal loss and neuroinflammation; a novel hydrogel was developed to address these issues.
- The hydrogel, called GC/I/E, incorporates Erythropoietin for rapid neuroprotection and angiogenesis, along with Mesoporous silica nanoparticles loaded with Interleukin-4 for sustained inflammation modulation.
- Experiments show that GC/I/E is biocompatible, reduces brain edema, improves vascular function, and enhances neuronal recovery, indicating its promising potential for treating TBI.
Advances in Understanding Diabetic Kidney Disease Progression and the Mechanisms of Acupuncture Intervention.
Int J Gen Med
November 2024
Nephropathy Department, The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang Province, People's Republic of China.
Article Synopsis
- Diabetic kidney disease (DKD) is kidney damage resulting from diabetes and is a major cause of chronic kidney disease globally, affecting both type 1 and type 2 diabetes patients.
- Early signs of DKD include microalbuminuria (small amounts of protein in urine) and high blood pressure, while advanced stages show more severe symptoms like massive protein leakage, low albumin levels, and significant swelling.
- Effective treatment focuses on managing blood sugar and pressure, reducing protein leakage, and preserving kidney function; acupuncture has shown potential benefits by helping regulate glucose, improve blood flow, and reduce inflammation.
Molecular characterization of circulating infectious bursal disease viruses in chickens from different Egyptian governorates during 2023.
Virol J
November 2024
Biotechnology Department, Faculty of Science, Cairo University, Giza, Egypt.
Infectious bursal disease virus (IBDV) induces severe immunosuppression in chickens, leading to significant economic losses in the global poultry industry. This study investigated 52 chicken flocks, including commercial broilers, layers, and baladi, from various Egyptian governorates in 2023. These flocks exhibited symptoms of depression, along with kidney and bursa lesions, indicative of IBDV infection.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!