AI Article Synopsis

  • Primary central nervous system lymphoproliferative disorders usually involve high-grade non-Hodgkin's lymphoma and can present as intracranial lesions.
  • A 56-year-old woman experienced new grand mal seizures, leading to the discovery of two dural-based lesions that resembled meningiomas on imaging.
  • Biopsy results showed benign reactive lymphoid tissue, marking the first documented case of intracranial pseudolymphoma presenting with seizures, emphasizing its importance in diagnosing symptomatic dural-based lesions.

Article Abstract

Primary central nervous system lymphoproliferative disorders comprise a heterogenous group of intracranial disease, predominantly of the high-grade non-Hodgkin's lymphoma type. We report a 56-year-old woman who developed new-onset grand mal seizures and was found to have two small uniformly enhancing dural-based lesions, which were radiologically concerning for meningiomas. Biopsy demonstrated findings consistent with benign, reactive lymphoid tissue. The patient's seizures resolved post-operatively. To our knowledge, this is the first reported patient with intracranial pseudolymphoma presenting as grand mal seizures. This case highlights this rare differential consideration in a patient with symptomatic dural-based lesion.

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http://dx.doi.org/10.1016/j.jocn.2013.06.025DOI Listing

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