The lectin ERGIC-53 goes viral.

Cell Host Microbe

Institute of Microbiology, University Hospital Center and University of Lausanne, 1011 Lausanne, Switzerland.

Published: November 2013

The biosynthesis of fusion-competent envelope glycoproteins (GPs) is a crucial step in productive viral infection. In this issue, Klaus et al. (2013) identify the cargo receptor endoplasmic reticulum (ER)-Golgi intermediate compartment 53 kDa protein (ERGIC-53) as a binding partner for viral GPs and a crucial cellular factor required for infectious virus production.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104956PMC
http://dx.doi.org/10.1016/j.chom.2013.10.014DOI Listing

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