The biosynthesis of fusion-competent envelope glycoproteins (GPs) is a crucial step in productive viral infection. In this issue, Klaus et al. (2013) identify the cargo receptor endoplasmic reticulum (ER)-Golgi intermediate compartment 53 kDa protein (ERGIC-53) as a binding partner for viral GPs and a crucial cellular factor required for infectious virus production.
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http://dx.doi.org/10.1016/j.chom.2013.10.014 | DOI Listing |
Sensors (Basel)
January 2025
Haute Ecole de Gestion Genève, HES-SO, 1227 Carouge, Switzerland.
Accurate localization is crucial for numerous applications. While several methods exist for outdoor localization, typically relying on GPS signals, these approaches become unreliable in environments subject to a weak GPS signal or GPS outage. Many researchers have attempted to address this limitation, primarily focusing on real-time solutions.
View Article and Find Full Text PDFMedicina (Kaunas)
January 2025
Sports and Exercise Medicine Division, Department of Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy.
: Accurate hiking time estimate is crucial for outdoor activity planning, especially in mountainous terrains. Traditional mountain signage and online platforms provide generalized hiking time recommendations, often lacking personalization. This study aims to evaluate the variability in hiking time estimates from different methods and assess the potential of a novel algorithm, MOVE, to enhance accuracy and safety.
View Article and Find Full Text PDFAntioxidants (Basel)
January 2025
Department of Experimental and Clinical Biomedical Sciences, University of Florence, 50134 Florence, Italy.
Background: Male professional soccer players frequently compete in multiple matches weekly, and each match significantly impacts their homeostasis, health, and performance. This study evaluates players response at 48 h post-match by combining biological and GPS data. Investigating biochemical and performance metrics offers insights into the physical demands of high-intensity exercise, essential for optimizing performance, recovery, and overall athlete health.
View Article and Find Full Text PDFSports (Basel)
January 2025
Sport Sciences Research Centre, Universidad Rey Juan Carlos, 28943 Fuenlabrada, Spain.
To enhance athletic performance and reduce the risk of injury, load quantification has allowed for a better understanding of the individual characteristics of the physical demands on soccer players during training or competition. In this regard, it appears crucial to summarize scientific evidence to provide useful information and future directions related to the speed and acceleration profiles of male soccer players. This review aims to evaluate the findings reflected in the available literature on both profiles in football, synthesizing and discussing data from scientific articles, while providing insights into quantification methods, employed thresholds, tracking systems, terminology, playing position, and microcycle day.
View Article and Find Full Text PDFCurr Oncol
December 2024
Department of Social Medicine, School of Medicine, University of Crete, 71500 Heraklion, Greece.
Lung cancer is the leading cause of cancer-related deaths worldwide, and delayed detection contributes to poor outcomes. Primary care plays a crucial role in early diagnosis, but detecting lung cancer early remains challenging for general practitioners (GPs). Therefore, the aim of this scoping review was to identify optimal strategies and pathways for lung cancer screening (LCS) in primary care settings globally.
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