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Trimodal thermal energy storage material for renewable energy applications.
Nature
December 2024
School of Chemistry, Monash University, Clayton, Victoria, Australia.
The global aim to move away from fossil fuels requires efficient, inexpensive and sustainable energy storage to fully use renewable energy sources. Thermal energy storage materials in combination with a Carnot battery could revolutionize the energy storage sector. However, a lack of stable, inexpensive and energy-dense thermal energy storage materials impedes the advancement of this technology.
View Article and Find Full Text PDFTrend of sales revenue by year for top selling cancer drugs in the US and the effect of loss of market exclusivity.
J Cancer Policy
December 2024
Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.
Biosimilars and generics have led to reduced cancer drug prices. The effect of biosimilar or generic drug competition on drug manufacturer revenue has not been previously described. In this study, the majority of top selling cancer drugs had a greater than 50 % decline in sales revenue within 2 years of generic or biosimilar market entry, reflecting both the decline in market share and reduction in unit drug price.
View Article and Find Full Text PDFGene therapies delivered through a single administration have revolutionized treatment possibilities for many patients living with serious or fatal conditions such as spinal muscular atrophy, hemophilia and sickle cell disease. However, shadowing the excitement about the transformational potential of many gene therapies has been widespread concern about the combination of uncertainty in the durability of their benefits over the long term and the short-term financial shock of high prices. As the healthcare payment ecosystem prepares for the growing number of gene therapies entering the market, three key interconnected challenges must be addressed: determining a fair price, managing clinical uncertainty and managing short-term budget impacts.
View Article and Find Full Text PDFPhysiologists as medical scientists: An early warning from the German academic system.
Physiol Rep
November 2024
Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg · Bad Krozingen, University of Freiburg, Freiburg, Germany.
"Medical scientists" are postgraduate investigators who are engaged in biomedical research, and either hold a biomedical PhD or are qualified in medicine but do not participate in patient care. Medical scientists constitute ~40% of staff at medical faculties and >90% at nonuniversity medical research institutions in Germany. However, medical scientists in Germany face limited long-term career prospects and a lack of dedicated training and support programmes.
View Article and Find Full Text PDFTuning metal-support interactions in nickel-zeolite catalysts leads to enhanced stability during dry reforming of methane.
Nat Commun
October 2024
Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.
Article Synopsis
- * This study introduces a method to improve the stability of these catalysts by anchoring nickel sites within dealuminated Beta zeolite, which enhances metal-support interactions.
- * Using advanced techniques like X-ray absorption spectroscopy and isotopic experiments, the research explains how the synthesis method increases the performance and durability of the Ni catalysts by reducing unwanted byproducts.
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