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http://dx.doi.org/10.1007/s00431-013-2202-5 | DOI Listing |
Transfus Clin Biol
August 2022
Quality management department, Croatian Institute of Transfusion Medicine, Zagreb, Croatia.
Thrombocytopenia with platelet count <50×10/L is common laboratory finding in a severely ill newborn in neonatal intensive care units (ICU). Neonates with severe thrombocytopenia are at risk of bleeding. Most dangerous is intracerebral hemorrhage (ICH) frequently leading to death or lifelong neurological sequels.
View Article and Find Full Text PDFZhonghua Wei Zhong Bing Ji Jiu Yi Xue
October 2018
Department of Pediatric Intensive Care Unit, Anhui Provincial Children's Hospital, Hefei 230051, Anhui, China. Corresponding author: Jin Danqun, Email:
Objective: To analyze the etiology and prognosis of children with thrombocytopenia (TP) in pediatric intensive care unit (PICU).
Methods: The data of children with TP (exclusion of congenital and unknown TP) admitted to PICU of Anhui Provincial Children's Hospital from January 2008 to December 2017 was analyzed retrospectively. According to the age of onset, the children were divided into infantile group (29 days to less than 1 year), early childhood group (1 to less than 3 years), preschool group (3 to less than 6 years), school age group (6 to less than 10 years) and puberty group (more than 10 years).
Eur J Pediatr
July 2013
Department of Paediatrics, Medical Center Alkmaar, Alkmaar, Netherlands.
Unlabelled: Ethylenediaminetetraacetic acid (EDTA)-dependent pseudothrombocytopenia (PTCP) is the phenomenon of a false low platelet count reported by an automated haematology analyzer due to in vitro aggregation of platelets. This aggregation is due to the interaction between antibodies and EDTA-dependent crypt antigens on platelets. We observed a new born child whose mother was diagnosed with transient PTCP due to transplacental transmission of maternal immunoglobulin G antibodies during pregnancy.
View Article and Find Full Text PDFPlatelets
February 2013
Department of Pediatrics, Hiroshima University Hospital, Minami-ku, Hiroshima, Japan.
EDTA-dependent pseudothrombocytopenia (PTCP) is characterised by a low platelet count caused by autoantibodies in the serum reacting with EDTA-anticoagulated blood. EDTA-dependent PTCP is caused by a factor that retains EDTA anticoagulation activity in the serum. We report here that a neonate from a mother with PTCP presented with transient low platelet counts when EDTA was used as an anticoagulant.
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