Cancer patients at a high risk of acquiring infectious diseases should be maintained in a facility where good infection control practices are followed. At our hospital, the infection control team(ICT)provides expertise, education, and support to the staff, helping them maintain proper standards, thereby minimizing the risks of infection. The ICT(established in 2004)has implemented infection control programs by employing an appropriate number of staff members after the revision of medical treatment fees in 2011. Our intervention program includes 2 general policies, namely, ordering and collection of blood cultures and intervention for the medical care of patients with positive blood cultures. In this study, we evaluated the effectiveness of our intervention for cancer patients with a positive blood culture. During the surveillance period(April 2011 to July 2012), 42 positive cases were determined to be infectious. ICT intervention was required in 37 cases. Our suggestions were accepted in 92%(34/37)of the cases, and improved outcome was estimated in 65%(22/34)of the cases. The results of our study contribute to the scientific bases on which routine clinical practices could be promoted in the future.
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PLoS Pathog
January 2025
LPHI, UMR 5294 CNRS/UM-UA15 Inserm, Université de Montpellier, Montpellier, France.
A sustained blood-stage infection of the human malaria parasite P. falciparum relies on the active exit of merozoites from their host erythrocytes. During this process, named egress, the infected red blood cell undergoes sequential morphological events: the rounding-up of the surrounding parasitophorous vacuole, the disruption of the vacuole membrane and finally the rupture of the red blood cell membrane.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Mathematics, University of Peshawar, Peshawar, Khyber Pakhtunkhwa, Pakistan.
In biology and life sciences, fractal theory and fractional calculus have significant applications in simulating and understanding complex problems. In this paper, a compartmental model employing Caputo-type fractional and fractal-fractional operators is presented to analyze Nipah virus (NiV) dynamics and transmission. Initially, the model includes nine nonlinear ordinary differential equations that consider viral concentration, flying fox, and human populations simultaneously.
View Article and Find Full Text PDFKlin Mikrobiol Infekc Lek
March 2024
Department of Microbiology, Olomouc University Hospital, Czech Republic, e-mail:
Objectives: Staphylococcus aureus is part of the human microbiota, but at the same time, it is capable of causing a wide range of diseases. Due to the ever-increasing resistance to antimicrobial agents and the existence of methicillin-resistant S. aureus (MRSA) strains, there is a real possibility of carrying even this resistant bacterium, which can subsequently cause a severe infection.
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January 2025
ARS, National Biological Control Laboratory, 59 Lee Road, Stoneville, MS, 38776, USA.
Aflatoxin contamination of corn can occur when developing kernels are infected by the plant pathogen Aspergillus flavus. One route of infection is from airborne conidia. We executed a series of experiments within the corn canopy during two growing seasons and in two states to document the abundance and dynamics of the airborne A.
View Article and Find Full Text PDFCell Biochem Biophys
January 2025
Department of Intensive Care Unit, Taizhou First People's Hospital, Taizhou, 318020, ZJ, China.
This study aims to explore the efficacy of neutrophil membrane nanovesicles (NMNVs) in the treatment of acute kidney injury caused by sepsis (S-AKI). Moreover, its effects on renal function indicators in plasma [creatinine (CREA), urea (UREA)], oxidative stress factor [malondialdehyde (MDA)], inflammatory factor [myeloperoxidase (MPO), histone H4 (H4), and macrophage inflammatory protein-2 (MIP-2)] are studied. Sixty SPF grade adult male Wistar rats in a healthy state under natural infection were randomly divided into blank, LSP, and experimental groups, with 20 rats in each group.
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