A Monte Carlo simulation is developed to model the physical sputtering of aluminum and tungsten emulating nanoscale focused helium and neon ion beam etching from the gas field ion microscope. Neon beams with different beam energies (0.5-30 keV) and a constant beam diameter (Gaussian with full-width-at-half-maximum of 1 nm) were simulated to elucidate the nanostructure evolution during the physical sputtering of nanoscale high aspect ratio features. The aspect ratio and sputter yield vary with the ion species and beam energy for a constant beam diameter and are related to the distribution of the nuclear energy loss. Neon ions have a larger sputter yield than the helium ions due to their larger mass and consequently larger nuclear energy loss relative to helium. Quantitative information such as the sputtering yields, the energy-dependent aspect ratios and resolution-limiting effects are discussed.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1088/0957-4484/24/49/495303 | DOI Listing |
Nucleic Acids Res
January 2025
Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland.
Designing RNA sequences that form a specific structure remains a challenge. Current computational methods often struggle with the complexity of RNA structures, especially when considering pseudoknots or restrictions related to RNA function. We developed DesiRNA, a computational tool for the design of RNA sequences based on the Replica Exchange Monte Carlo approach.
View Article and Find Full Text PDFSoc Networks
January 2024
Departments of Sociology, Statistics, Computer Science, and EECS, University of California, Irvine, CA, United States.
The exponential-family random graph models (ERGMs) have emerged as an important framework for modeling social networks for a wide variety of relational types. ERGMs for valued networks are less well-developed than their unvalued counterparts, and pose particular computational challenges. Network data with edge values on the non-negative integers (count-valued networks) is an important such case, with examples ranging from the magnitude of migration and trade flows between places to the frequency of interactions and encounters between individuals.
View Article and Find Full Text PDFLangmuir
January 2025
College of Chemical Engineering, State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing 211816, PR China.
Clarifying the potential relationship between the microstructure of nanoconfined choline chloride/urea (ChClU) and CO absorption performance is key to understanding the abnormal increase in CO under nanoconfinement. In this study, we used molecular dynamics simulations and grand canonical Monte Carlo (GCMC) to systematically study the mechanism underlying the absorption of CO by ChClU within nanoslits. According to the spatial distribution, ChClU can form two different laminar regions within nanoslits, namely, the interfacial region (region I) and beyond region I (region II).
View Article and Find Full Text PDFEnviron Pollut
January 2025
Oncologic Network, Prevention and Research Institute (ISPRO) - Health Service of Tuscany, Via Cosimo il Vecchio 2, Florence, 50139, Italy.
Outdoor air pollution is a significant risk factor for tracheal, bronchus, and lung (TBL) cancer. This study employs a Bayesian approach to evaluate TBL cancer mortality due to air pollution in Tuscany, Central Italy, in 2023. Using locally validated data, we assessed the impact of fine particulate matter (PM and PM) and nitrogen dioxide (NO) in terms of attributable deaths and years of life lost (YLL).
View Article and Find Full Text PDFClin Microbiol Infect
January 2025
Université Paris Cité and Université Sorbonne Paris Nord, Inserm, IAME, F-75018 Paris, France; Unité Fonctionelle de Pharmacologie, GHU Paris Seine Saint-Denis, Assistance Publique-Hôpitaux de Paris (APHP), Université Sorbonne Paris Nord, Bondy, France.
Objectives: The aim of the present study was to develop a PK interaction model of intravenous (IV) and oral clindamycin when combined with rifampicin, and to determine whether appropriate clindamycin concentrations could be achieved for different doses and administration routes (oral, intermittent and continuous infusion) of clindamycin.
Methods: Five hundred and eighteen plasma samples were prospectively obtained from 124 patients treated for bone and joint infections. Population PK analysis was performed using Monolix software.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!