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Clinical characteristics and managements of congenital hepatic hemangioma: a cohort study of 211 cases.
Hepatol Int
November 2024
Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu, 610041, China.
Article Synopsis
- This study focused on congenital hepatic hemangiomas (CHHs) in children, investigating their clinical characteristics and how management strategies have changed over the past two decades.
- A total of 211 patients were analyzed, identifying four subtypes of CHHs, with most patients experiencing different rates of involution (size reduction) of the hemangiomas based on their subtype.
- The research revealed a significant increase in the use of expectant management (monitoring without invasive treatment), rising from 35.4% to 77.7% from 2003-2012 to 2013-2022, while maintaining a high survival rate of 98.6% among patients.
Diagnosing Common Benign Skin Tumors.
Am Fam Physician
October 2024
Prisma Health and the University of South Carolina School of Medicine, Greenville.
Article Synopsis
- Distinguishing between benign and potentially malignant skin tumors is crucial in family medicine, and many benign tumors can be diagnosed based on their history, appearance, and growth patterns.
- Procedures like biopsy or excision may be necessary if there's uncertainty about a diagnosis or if the lesion changes rapidly.
- Treatment options vary based on the type of lesion and patient preference, with methods like excision, laser therapy, and cryotherapy commonly used; special considerations are needed for patients with darker skin to minimize risks like hypopigmentation.
The molecular chronology of mammary epithelial cell fate switching.
bioRxiv
November 2024
Department of Surgery, Medical College of Wisconsin Cancer Center, Milwaukee, WI, USA.
The adult mammary gland is maintained by lineage-restricted progenitor cells through pregnancy, lactation, involution, and menopause. Injury resolution, transplantation-associated mammary gland reconstitution, and tumorigenesis are unique exceptions, wherein mammary basal cells gain the ability to reprogram to a luminal state. Here, we leverage newly developed cell-identity reporter mouse strains, and time-resolved single-cell epigenetic and transcriptomic analyses to decipher the molecular programs underlying basal-to-luminal fate switching .
View Article and Find Full Text PDFDetermination of the impacts of supplemental dietary curcumin on post-partum uterine involution using pulsed-wave doppler ultrasonography in Zaraibi goat.
BMC Vet Res
July 2024
Theriogenology Department, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.
This study aimed to evaluate the impacts of supplemental dietary curcumin on post-partum uterine involution using pulsed-wave Doppler ultrasonography in postpartum goats. Ten pluriparous Zaraibi goats were used and divided into two groups. Group 1 (n = 5; control) received only a base diet.
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