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Normal tissue complication probability model for severe radiation-induced lymphopenia in patients with pancreatic cancer treated with concurrent chemoradiotherapy.
Phys Imaging Radiat Oncol
January 2025
Department of Radiation Oncology, Hokkaido University Faculty of Medicine and Graduate School of Medicine, North 15 West 7, Kita-ku, Sapporo, Hokkaido 060-8638, Japan.
Background And Purpose: Radiation-induced lymphopenia (RIL) may be associated with a worse prognosis in pancreatic cancer. This study aimed to develop a normal tissue complication probability (NTCP) model to predict severe RIL in patients with pancreatic cancer undergoing concurrent chemoradiotherapy (CCRT).
Materials And Methods: We reviewed pancreatic cancer patients treated at our facility for model training and internal validation.
Effect of Radiotherapy on the Type and Timing of Breast Reconstruction After Mastectomy in Breast Cancer Patients.
Sisli Etfal Hastan Tip Bul
December 2024
Department of Plastic and Reconstructive Surgery, Memorial Hospital, Istanbul, Türkiye.
Breast cancer is the most common cancer type among women according to the World Health Organization data. While breast-conserving surgery has been increasingly performed in patients with early-stage breast cancer, unilateral or bilateral mastectomy is still performed in many patients. With the changes in mastectomy techniques and the development of breast reconstruction techniques over the years, today the aim of breast reconstruction is to create breast tissue in a shape and symmetry that will correct the anatomical defect that occurs after mastectomy, without affecting the patient's oncological treatment.
View Article and Find Full Text PDFAberrant functional connectivity between the retrosplenial cortex and hippocampal subregions in amnestic mild cognitive impairment and Alzheimer's disease.
Brain Commun
December 2024
Department of Radiology, Aerospace Center Hospital, Beijing 100049, China.
The posterior cingulate cortex and hippocampus are the core regions involved in episodic memory, and they exhibit functional connectivity changes in the development and progression of Alzheimer's disease. Previous studies have demonstrated that the posterior cingulate cortex and hippocampus are both cytoarchitectonically heterogeneous regions. Specifically, the retrosplenial cortex, typically subsumed under the posterior cingulate cortex, is an area functionally and anatomically distinct from the posterior cingulate cortex, and the hippocampus is composed of several subregions that participate in multiple cognitive processes.
View Article and Find Full Text PDFBilateral hip exoskeleton assistance enables faster walking in individuals with chronic stroke-related gait impairments.
Sci Rep
January 2025
The BioRobotics Institute, Scuola Superiore Sant'Anna, Pontedera, Pisa, Italy.
Millions of individuals surviving a stroke have lifelong gait impairments that reduce their personal independence and quality of life. Reduced walking speed is one of the major problems limiting community mobility and reintegration. Previous studies have shown positive effect of robot-assisted gait training utilizing hip exoskeletons for individuals with gait impairments due to a stroke, leading to increased walking speed in post-treatment compared to pre-treatment assessments.
View Article and Find Full Text PDFCompartmental location of middle ear inflammatory polyps in cats: 9 cases (2021-2023).
J Small Anim Pract
January 2025
Surgical Unit, Centre Hospitalier Vétérinaire St Martin, Allonzier La Caille, France.
Objectives: To report the compartmental location of feline aural inflammatory polyps within the tympanic bulla.
Materials And Methods: Nine client-owned cats with clinical signs and middle ear filling consistent with feline aural inflammatory polyps were prospectively pre-selected and underwent unilateral or bilateral ventral bulla osteotomy. Preoperative and surgical findings, complications and outcomes were recorded.
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