Oral foregut cyst in a neonate.

J Craniofac Surg

From the *Federal University of Tocantins, Palmas, Tocantins, †São Leopoldo Mandic Institute and Research Center, Campinas, São Paulo; ‡General Public Hospital of Palmas; and §Dona Regina Public Maternity Hospital, Palmas, Tocantins, Brazil.

Published: November 2013

Oral foregut cysts are congenital choristomas that arise in the oral cavity during embryonic development from remnants of foregut-derived epithelium. This is an unusual report of a neonate with a large congenital sublingual cystic lesion, extending superficially from the left ventral tongue to the anterior floor of the mouth, impeding breast-feeding. The differential diagnosis included dermoid cyst, epidermoid cyst, mucous retention cyst, and oral lymphangioma. The treatment of choice was enucleation under general anesthesia. Histology showed a cystic lesion with a ciliated pseudostratified columnar epithelium with numerous goblet cells. Immunohistochemistry was positive for cytokeratin 7 and thyroid transcription factor 1 and negative for cytokeratin 20, resulting in a final diagnosis of an oral foregut cyst. Three weeks after surgery, the tongue had healed with good mobility, and breast-feeding could be established. No recurrence was present at 6 months of follow-up.

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http://dx.doi.org/10.1097/SCS.0b013e31829af985DOI Listing

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