Background: The aim of this study was to assess the influence of ridge morphology on the amount of horizontal bone augmentation achieved with the sandwich bone augmentation (SBA) technique in the reconstruction of buccal dehiscence defects on dental implants.
Methods: Cone beam computed tomography (CBCT) was used to assess bone width changes in 26 patients who participated in a randomized controlled trial conducted in 2008 to 2011. The amount of horizontal bone gain was evaluated at four different levels (3, 6, 9, and 12 mm apical to the alveolar crest) and three different time points (T1: baseline, T2: at time of graft placement, and T3: 6 months later). Different morphological characteristics of the alveolar ridge were also evaluated to determine their influence on horizontal bone augmentation. A total of 78 CBCT scans were assessed.
Results: Comparison of the changes in ridge morphology at all measurement locations showed an overall ridge width gain of 2.30 ± 2.20 mm after 6 months. The use of membranes and the angulation of the concavity played a role in influencing the outcomes of the SBA technique. Critical crest angulation (CA) is 150° for bone gain at 9 mm apical to the crest. When CA is smaller than 150°, the horizontal bone gain was 4.3 ± 2.2 mm; if CA is greater than 150°, the gain was significantly lower at 1.3 ± 1.7 mm (p = .001).
Conclusions: SBA is a reliable and predictable technique to gain horizontal ridge width with simultaneous implant placement. Crest ridge angulation can be used as a tool to predict bone gain at 9 mm apical to the bone crest.
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http://dx.doi.org/10.1111/cid.12174 | DOI Listing |
Front Pharmacol
December 2024
College of Animal Science and Technology, Jilin Agricultural University, Changchun, China.
Background: Sika deer (, 1838) antler is a highly esteemed tonic renowned for its abundant assortment of polypeptides, polysaccharides, amino acids, and minerals, and is recognized for its multifarious pharmacological properties. However, limited research has been conducted regarding the variation in composition of deer antlers between the upper and basal sections, as well as their pharmacological effects on immunological activity and anti-fatigue in mice. The objective of this study was to conduct a comprehensive analysis on the appearance, chemical composition, and pharmacological effects of different components within sika deer antlers.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Physiology, Spinal Cord and Brain Injury Research Center, University of Kentucky College of Medicine, Lexington, KY, 40536, USA.
Spinal cord injury (SCI) leads to permanent motor and sensory loss that is exacerbated by intraspinal inflammation and persists months to years after injury. After SCI, monocyte-derived macrophages (MDMs) infiltrate the lesion to aid in myelin-rich debris clearance. During debris clearance, MDMs adopt a proinflammatory phenotype that exacerbates neurodegeneration and hinders recovery.
View Article and Find Full Text PDFAm J Orthod Dentofacial Orthop
January 2025
Department of Orthodontics, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic; Department of Dentistry, First Faculty of Medicine, Charles University and the General University Hospital, Prague, Czech Republic. Electronic address:
Introduction: The primary aim of this study was to assess the amount and long-term stability of orthodontically created bone in patients with agenesis of maxillary lateral incisors after canine distalization. The secondary aim was to explore the impact of patient age on the process of alveolar bone resorption.
Methods: A group of patients with agenesis of the maxillary permanent lateral incisor was examined at 4 time points: the beginning of orthodontic treatment (T1, n = 80), the end of treatment (T2, n = 80), 2-5 years after treatment (T3, n = 79), and 12-15 years after treatment (T4, n = 32).
Clin Rheumatol
December 2024
Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, 230032, Anhui, China.
Population-based studies have been inconsistent in terms of the relationship between bone mineral density (BMD) and the progression of osteoarthritis. This study aimed to evaluate the causal relationship between BMD and the risk of joint replacement in patients with osteoarthritis. We performed a two-sample Mendelian randomization (MR) analysis to determine the association of BMD of the total body, femoral neck, and lumbar spine with the risk of hip and knee replacements.
View Article and Find Full Text PDFJ Dent
December 2024
Periodontology Unit, Centre for Host Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, United Kingdom. Electronic address:
Introduction And Objectives: Clinical studies have shown favorable outcomes following use of platelet rich fibrin (PRF), either alone or in conjunction with biomaterials for alveolar ridge reconstruction (ARR) or guided bone regeneration (GBR) . While PRF application accelerates wound healing and reduces postoperative discomfort, its effects on the alveolar bone gain, as part of ARR or GBR is less clear. Therefore, this study aims to investigate the clinical effectiveness of PRF when used in ARR or GBR, as well as postoperative discomfort following these procedures.
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