Background: Squamous cell carcinoma (SCC) is the most common oral cavity malignant tumor. Surgery, radiotherapy, and chemotherapy have been the major options for its treatment. Electrochemotherapy (ECT) is a novel local treatment successfully used in secondary or primary skin or subcutaneous tumors. This new cancer treatment is a modality in which a locally applied electrical field enhances cell membrane permeability, thereby allowing greater intracellular accumulation of a chemotherapeutic agent.
Methods: We report a case of a man affected by an ulcerated SCC. The man was treated with ECT with good results.
Results: In our case, ECT was successful in the management of extensive metastasis of SCC in clinical conditions, whereas other approaches were rejected.
Conclusion: This case shows good clinical results; however, other studies are necessary to show that ECT should be considered as a promising treatment option.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258086 | PMC |
| http://dx.doi.org/10.1002/hed.23552 | DOI Listing |
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