AI Article Synopsis
- The study investigates early onset multiple sclerosis (MS) in Brazilian patients diagnosed before age 18, highlighting the challenges in diagnosis and management.
- Data was collected retrospectively from 20 MS units across 11 states, resulting in 117 cases, with a mean onset age of 13.7 years and an average disease duration of 10 years.
- Overall, while some cases were severe, most patients with pediatric MS in Brazil exhibited relatively mild symptoms, with low disability levels and an average relapse rate of one episode every 2.5 years.
Article Abstract
Multiple sclerosis (MS) starting in childhood and adolescence poses a challenge for diagnosis and management of the disease. The aim of the present study was to assess the characteristics of early onset MS in Brazilian patients. Methods Retrospective data collection from specialized MS units. Results From 20 MS units in 11 Brazilian states, 117 cases of MS starting before the age of 18 years were collected. These patients had an average of 10 years of disease duration, still typically with low disability and one relapse every 2.5 years. The mean age for disease onset was 13.7 years. Conclusion The present study introduces a large series of Brazilian cases of pediatric MS. Although some patients presented a very severe form of MS, on the whole the group of patients with MS starting in childhood or adolescence presented a relatively mild form of this disease in Brazil.
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| http://dx.doi.org/10.1590/0004-282X20130122 | DOI Listing |
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